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Dual-band fibered confocal fluorescence microscope for the intravital interrogation of deep tissues and organs in real time and with cellular resolution KU Leuven

Greetje Vande Velde
Biomedical MRI, Molecular Immunology (Rega Institute), Microbial and Plant Genetics (CMPG), Laboratory for Clinical Infectious and Inflammatory Disorders, Translational Research in GastroIntestinal Disorders, Laboratory of Clinical Microbiology
MoSAIC, the KU Leuven core facility for non-invasive live animal imaging, is currently the only center in Flanders (and Belgium) that is operating an intravital fibered confocal fluorescence microscope (FCFM). This technology is unique in that it allows to image fluorescently labeled cells, processes and structures that are located in deeper sites, tissues and organs, in real-time and with cellular resolution. Because it is minimally ...

Modular Confocal Raman Microscope Ghent University

Andre Skirtach
Department of Animal production, Department of Molecular biotechnology, Department of Information technology

The envisioned equipment comprises of a modular confocal Raman microscope for bio-imaging and identification of (bio-)molecules (molecular fingerprinting). The setup includes a microscope body with positioning stage, Nd-YAG laser, detectors and spectrometers as well as a sensitive Peltier-cooled CCD camera and allows for visualizing chemical properties with diffraction limited resolution.

Replacement of confocal fluorescence microscope for visualisation of biological processes in humans and animals Ghent University

Hans Nauwynck
Department of Veterinary and Biosciences, Department of Translational Physiology, Infectiology and Public Health, Department of Internal Medicine, Reproduction and Population Medicine

The confocal fluorescence microscope Leica TCS SP2 Laser Scanning Spectral Confocal System, localized in the Laboratory of Virology, Faculty of Veterinary Medicine is a device that is daily used by different users of the Faculties of Veterinary Medicine and Medicine and Health Sciences for the research on different biological processes (pathogenesis, immunopathology, embryology, …). It is the only confocal microscope at the Faculty of ...

Laser bench for laser scanning confocal microscopy Ghent University

Kevin Braeckmans
Department of Pharmaceutics

Confocal laser scanning microscopy is a widespread technique in the life sciences to record high-quality images of biological specimen. Laser illumination is used to excite fluorescent markers in biological samples. In this project budget is requested to replace the laser illumination system of a heavily used confocal microscope, as it is getting near the end of its lifetime.

AQ²UABIT – Advanced Qualitative and QUantitative surface Analysis of BITuminous binders using laser scanning confocal microscopy. University of Antwerp

Wim Van den bergh
Energy and Materials in Infrastructure and Buildings (EMIB)
In this project, an innovative methodology is developed by using Laser Scanning Confocal Microscope (LSCM) to investigate the behaviour of bituminous binders and mortar under specific physical and mechanical conditions including the impact of several additives. Bitumen, an oil derivate, is an important binder used in asphalt mixtures, roofing materials and emulsions. Regarding the circular economy, a higher recycling rate and increased service ...

Confocal laser scanning microscopy for infertility and stem cell research Ghent University

Petra De Sutter
Department of Human Structure and Repair, Department of Uro-gynaecology, Department of Internal Medicine, Reproduction and Population Medicine

The Fluoview FV3000 (Olympus, Belgium) is a self-contained confocal laser scanning fluorescence microscope, that allows for capturing confocal images that can be modified and studied on later on. For the different research topics that we are currently studying, confocal imaging is a frequently used tool to analyze our data both for clinical (diagnosis) and research purposes.

Quantitative automatic analysis of confocal digital images of the cornea Ghent University

Wilfried Philips
Department of Telecommunications and information processing

This proposal aims to develop and validate algorithms for image quality improvement, segmentation and extraction of clinically relevant parameters, for automated quantitative analysis of confocal digital images of the cornea. This is done to reduce the analysis time and to avoid subjective errors associated with manual, or a semi-automatically work made by the medical specialist.

Novel microscope designs for fast and highly adaptable fluorescence microscopy. KU Leuven

Wim Vandenberg
Biochemistry, Molecular and Structural Biology
Due to its high sensitivity and specificity, fluorescence microscopy has been a workhorse technique in (bio-)chemical and medical research for several decades. In recent years, thanks to advances in labeling chemistry, the problems to which this technique can be applied have been strongly diversified. However, the application of these new technologies in 3D rather than 2D microscopy has been limited, at least in part due to a lack ...

The next generation of transmission electron microscopy: from biomedicine to nanomaterials. A state-of-the art electron microscopy system for cryo-EM and correlative light and electron microscopy Hasselt University

Ivo LAMBRICHTS
Cardio & organ systems
This application was submitted by a consortium from different research institutes at Hasselt University in order to reinforce their research lines, to strengthen collaborations within Hasselt University and with external partners. This state-ofthe- art infrastructure will enable us to become important (international) players in the field of cryo-EM/CLEM since such infrastructure has only limited presence in Flanders and Belgium. The requested ...

Advanced Centre for Advanced Microscopy (ACAM). University of Antwerp

Jean-Pierre Timmermans
Laboratory of cell biology and histology
The Antwerp Centre for Advanced Microscopy (ACAM) provides high-end service for visualizing biological samples from the nano- to the mesoscale. Its mission is to be the go-to hub for demanding microscopy-oriented work and to exploit its quantitative imaging expertise to foster research excellence at the University of Antwerp. To do so, ACAM assists with project planning, sample preparation, microscope selection and use, image analysis and ...