Researcher
Kevin Braeckmans
- Keywords:nanomedicines, biophotonics, medical nanotechnology, drug delivery, microscopy
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Nanophotonics, Nanometrology, In vitro testing, Biopharmaceuticals, Non-clinical studies, Nanomaterials, Medical nanotechnology, Biopharmaceutics, Physical pharmacy
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Aug 1999 → Today
Infrastructure
1 - 6 of 6
- Flanders BioImaging (Consortium partner)
- A multimodal non-linear optical platform for 2l3-photon excitation and 2ndl3rd harmonic imaging deep inside living tissues and animals (Consortium partner)
- Confocal and two-photon Microscope (Consortium coordinator)
- Stimulated Emission Depletion Microscope (Consortium coordinator)
- Nikon Spinning Disk CSU-X1 Microscope
- NanoSight LM10 (Nanoparticle characterisation)
Projects
1 - 10 of 60
- Uncovering the mechanism underlying and consequences of alphaherpesvirus-induced formation of tunneling nanotubes (TNTs)From1 Nov 2024 → TodayFunding: FWO fellowships
- Upgrade of confocal FLIM microscope with two-photon excitation and detection modulesFrom1 May 2024 → TodayFunding: FWO Medium Size Research Infrastructure
- Drug loading and genetic engineering of mesenchymal stem cells through photoporation for the treatment of glioblastoma and osteoarthritisFrom1 Jan 2024 → TodayFunding: BOF - projects
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Photoporation of fluorescent nanobodies for super resolution imaging and structure-function analysis of immune and cancer cell invadosomes.From1 Nov 2023 → TodayFunding: FWO fellowships
- Analysis and prevention of protein particle formation – An approach towards safer antibody drugs in the clinicFrom1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Engineering of universal iPSC-derived therapeutic cells by nanofiber photoporation.From1 Oct 2023 → 31 Oct 2023Funding: BOF - doctoral mandates
- Uncovering the mechanism underlying and consequences of alphaherpesvirus-induced formation of tunneling nanotubes (TNTs)From1 Oct 2023 → 31 Oct 2024Funding: BOF - doctoral mandates
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- Evaluation of cellular dynamics using automated widefield imagingFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
Publications
1 - 10 of 249
- Porcine ex-vivo intestinal mucus has age-dependent blocking activity against transmissible gastroenteritis virus(2024)
Authors: Waqar Saleem, Nathan Carpentier, Charlotte Hinnekens, Dayoung Oh, Sandra Van Vlierberghe, Kevin Braeckmans, Hans Nauwynck
- Laser-induced vapor nanobubbles for B16-F10 melanoma cell killing and intracellular delivery of chemotherapeutics(2024)
Authors: Jana Ramon, Yanou Engelen, Herlinde De Keersmaecker, Ilia Goemaere, Deep Punj, Julián Mejía Morales, Cédric Bonte, Geert Berx, Esther Hoste, Stephan Stremersch, et al.
Pages: 1019 - 1036 - Photoporation-mediated spatial intracellular delivery of stem cell-derived cardiomyocytes(2024)
Authors: Laurens Léger, Chloë De Clercq, Jeffrey Aalders, Kiara Van Acker-Verberckt, Kevin Braeckmans, Jolanda van Hengel
- Nucleic acid degradation as barrier to gene delivery : a guide to understand and overcome nuclease activity(2024)
Authors: Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan De Smedt, Katrien Remaut
Pages: 317 - 360 - Non-viral delivery of RNA for therapeutic T cell engineering(2024)
Authors: Dominika Berdecka, Stefaan De Smedt, Winnok H. De Vos, Kevin Braeckmans
- Designing of gradient scaffolds and their applications in tissue regeneration(2023)
Authors: Ananya Pattnaik, A. Swaroop Sanket, Sanghamitra Pradhan, Rajashree Sahoo, Sudiptee Das, Swarnaprbha Pany, Timothy E. L. Douglas, Rambabu Dandela, Qiang Liu, Jaykumar Rajadas, et al.
- Immunotherapy : towards engineered NK cell therapy : mRNA transfection of NK92 cells by photoporation with biodegradable polydopamine nanosensitizersHOTOPORATION WITH BIODEGRADABLE POLYDOPAMINE NANOSENSITIZERS(2023)Volume: 25
Authors: Charlotte Hinnekens, Aranit Harizaj, Ilia Goemaere, Stefaan De Smedt, Bart Vandekerckhove, Juan Carlos Fraire, Kevin Braeckmans
Pages: S228 - S228 - Novel opto-fluidic drug delivery system for efficient cellular transfection(2023)
Authors: Majid Layachi, Anthony Treizebré, Laurent Hay, David Gilbert, Jean Pesez, Quentin D’Acremont, Kevin Braeckmans, Quentin Thommen, Emmanuel Courtade
- Porcine intestinal mucus has an age-dependent blocking activity against a porcine coronavirus (Transmissible Gastroenteritis Virus)(2023)
Authors: Waqar Saleem, Nathan Carpentier, Charlotte Hinnekens, Sandra Van Vlierberghe, Kevin Braeckmans, Hans Nauwynck
Pages: 42 - 42 - Photothermal nanomaterial-mediated photoporation(2023)
Authors: Ranhua Xiong, Félix Sauvage, Juan Carlos Fraire, Chaobo Huang, Stefaan De Smedt, Kevin Braeckmans
Pages: 631 - 643
Patents
1 - 9 of 9
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method to increase the permeability of the plasma membrane of cells and a structure suitable for use in such method (Inventor)
- Method and device to provide a microfluidic flow (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Composition comprising at least one nanobomb suitable for altering a biological barrier (Inventor)
- Composition for treatment of vitreous disease or disorder (Inventor)
- Method and system for characterizing extracellular vesicles (Inventor)
- Method and system for dispersion measurements (Inventor)