Studying biomolecular corona-dependency of (sub)cellular interactions using patient-derived tumor models to guide ev-based therapeutic development. Ghent University
Extracellular vesicles (EV) are complex nanoparticles required for the intercellular transfer of diverse biological cargoes. Exploitation of EV as advanced drug delivery systems has sparked general interest both in academia and industry for the treatment of a multitude of diseases including cancer. However, the clinical application of EV-based therapeutics is hampered by the lack of knowledge on their (sub)cellular interactions and the ...