Research Group for Neurobiology and Gene Therapy
The laboratory for Neurobiology and Gene Therapy is committed to gain insight in the underlying pathology of Parkinson's Disease (PD) and more recently Multiple System Atrophy (MSA), on both the molecular and cellular level. We are specifically focussing on the proteins α-synuclein and LRRK2, two key players in sporadic and familial PD. The underlying idea is that better disease models and insights in the molecular pathogenesis are required to develop novel causal therapeutic strategies that can cure or slow down the disease. We make use of viral vector technology and molecular imaging as core technologies to support our research and to develop and characterize new cellular and rodent disease models. Finally, we are also investing in pre-clinical drug discovery through our neuro drug discovery platform.