Projects
Towards the realization of a structural biology platform at the University of Antwerp: The Mosquito Xtal3 crystallization robot as the missing link. University of Antwerp
Structural biology of Interleukin-34, a novel cytokine ligand for colony stimulating factor 1 receptor (CSF-1R) Ghent University
We propose an interdisciplinary research project at the frontline of molecular structural biology to dissect the interaction of a novel cytokine, interleukin 34, with its hematopoietic RTKIII receptor, Colony Stimulating Factor1 Receptor. The proposed research project aims to elucidate the structural, kinetic and thermodynamic determinants that dictate this unusual cytokinereceptor specificity, using both experimental and computational ...
The structural biology of Interleukin-34, a novel cytokine-ligand for the colony stimulating factor 1 receptor (CSF1R) Ghent University
We propose an interdisciplinary research project at the frontline of molecular structural biology to dissect the interaction of a novel cytokine, Interleukin-34; with its hematopoietic RTKIII receptor, Colony Stimulating Factor-1 Receptor. The proposed research project aims to elucidate the structural, kinetic and thermodynamic determinants that dictate this unusual cytokine-receptor specificity, using both experimental and computational ...
SRP-Onderzoekszwaartepunt: Towards Exploratory and Time-Resolved Structural Biology Vrije Universiteit Brussel
Nanobodies for structural biology, molecular pharmacology and drug discovery Vrije Universiteit Brussel
Merging immunology with synthetic biology to improve animal health: strain engineering for the production of structurally defined carbohydrates with immunomodulating properties Ghent University
The continued spread of anti-microbial resistant bacterial pathogens together with a lag in the development of suitable antibiotic alternatives set the alarm bells ringing in public and animal health. In this project proposal, ImmunoKeys, synthetic biology and animal immunology experts join forces to engineer microbial cell factories capable of producing structurally well-defined (partially acetylated) chitooligosaccharides with optimal ...
Connecting the molecular structure and function of P4/P5B transport ATPases to neuronal cell biology KU Leuven
Research in the Laboratory of Cellular Transport Systems (Department of Cellular and Molecular Medicine; KU Leuven) focuses on P-type transport ATPases in mammalian organism including their role in human neurodegenerative diseases such as Parkinson’s disease. P-type ATPases are transport proteins that generate vital ion or lipid gradients across the plasma membrane or organellar membranes of nearly every cell in the organism. Our current ...