< Back to previous page
Project
Developoing new tools for (un)structural biology by ion mobility-mass spectrometry and related methods..
In our research we will use state-of-the-art 'native' mass spectrometric techniques to investi-gate both the dynamic as well as structural characteristics of membrane (associated) proteins. Furthermore will we probe the changes in conformational space of proteins when they interact with ligand or other proteins using ion mobility-mass spectrometry, with a special focus on intrinsically disordered proteins.
Date:1 Oct 2012 → 31 Jan 2016
Keywords:ION MOBILITY SPECTROMETRY, NATIVE MASS SPECTROMETRY, INTRISICALLY DISORDERED PROTEINS, MEMBRANE PROTEINS
Disciplines:Medicinal and biomolecular chemistry, Biochemistry and metabolism, Molecular and cell biology, Plant biology, Systems biology, Biophysics, Medical biochemistry and metabolism