Researcher
Arnout Voet
- Disciplines:Biochemistry and metabolism, Systems biology, Medical biochemistry and metabolism
Affiliations
- Biochemistry, Molecular and Structural Biology (Division)
Member
From1 Nov 2004 → Today
Projects
1 - 10 of 42
- AI-guided computational design of anti-virulence proteins as sustainable alternative antibacterialsFrom1 Oct 2024 → TodayFunding: BOF - projects
- AI-Driven Analysis and Design of Protein-Ligand Interactions for Advancing De Novo Drug DiscoveryFrom23 Jul 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Valorizing the SymBody Platform for Ultra-stable Biopharmaceuticals through an EIC Pathfinder Open project application.From1 May 2024 → TodayFunding: IOF - mandates
- ULtra-high Throughput screening of Microbial metabolites using Echo-MS (ULTiMatE-MS)From1 May 2024 → TodayFunding: FWO Medium Size Research Infrastructure
- Symibs: a new class of designer intrabodies for the development of anticancer treatments targeting unstructured protein domains of MYC and p53.From1 Nov 2023 → TodayFunding: FWO Strategic Basic Research Grant
- Second generation lactic acid as a renewable platform for a circular bioeconomy (LAPLACE)From1 Oct 2023 → TodayFunding: FWO Strategic Basic Research (SBO)
- Integrated Strategy for Microbial Production of Lactic Acid and Ethyl Lactate from 2G FeedstockFrom28 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Computational design of a symmetric scaffold protein for small molecule biosensingFrom5 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting the androgen receptor dimerisation via computer-aided drug design and high throughput synthesis for prostate cancer therapy.From1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Design of self-assembled 2D layers based on artificial α/β propeller building blocksFrom1 Sep 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 106
- Discovery of a novel androgen receptor antagonist, MEL-6, with stereoselective activity and optimization of its metabolic stability(2024)
Authors: Christine Helsen, Steven Joniau, Arnout Voet, Wim Dehaen, Frank Claessens
- Rational evolution for altering the ligand preference of estrogen receptor alpha(2024)
Authors: Xiao Yin Lee, Anton Gorkovskiy, Karin Voordeckers, Els Henckaerts, Vitor Bernardes Pinheiro, Frank Claessens, Kevin Verstrepen, Arnout Voet, Christine Helsen
- Insights in inulin binding and inulin oligosaccharide formation by novel multi domain endo-inulinases from Botrytis cinerea(2024)
Authors: Arnout Voet, Wim Van den Ende
- Exploration of 1,2,3-triazolo fused triterpenoids as inhibitors of human coronavirus 229E targeting the viral nsp15 protein(2024)
Authors: Annelies Stevaert, Benjamin Van Loy, Arnout Voet, Lieve Naesens, Wim Dehaen
- Human Autosomal Recessive DNA Polymerase Delta 3 Deficiency Presenting as Omenn Syndrome(2024)
Authors: Bethany Pillay, Lisa Ehlers, Selket Delafontaine, Xavier Bossuyt, Arnout Voet, Stefaan Soenen, Giorgia Bucciol, Stephanie Humblet-Baron, Leen Moens, Isabelle Meyts
- Rational Design and Functionalization of an Artificial Scaffold Protein for Synthetic Biochemistry(2023)
Authors: Staf Wouters, Arnout Voet, Johan Robben
- Intracellular BAPTA directly inhibits PFKFB3, thereby impeding mTORC1-driven Mcl-1 translation and killing MCL-1-addicted cancer cells(2023)
Authors: Flore Sneyers, Martijn Kerkhofs, Rita La Rovere, Arnout Voet, Mieke Dewerchin, Bart Ghesquière, Geert Bultynck
- Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents(2023)
Authors: Eveline Vriens, Dries De Ruysscher, Sofie Dekimpe, Gert Steurs, Ahmed Shemy, Dirk Daelemans, Arnout Voet, Wim De Borggraeve, Eveline Lescrinier, Joleen Masschelein
- A widely applicable and cost-effective method for specific RNA-protein complex isolation(2023)
Authors: Roosje Van Ende, Arnout Voet, Koen Geuten
- Study of novel androgen receptor V770 variant in androgen insensitivity syndrome patients reveals the transitional state of the androgen receptor ligand binding domain homodimer(2023)
Authors: Christine Helsen, Xiao Yin Lee, Arnout Voet, Frank Claessens
Patents
1 - 6 of 6
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)