Researcher
Niek Sanders
- Keywords:drug delivery, immunology, gene therapy, cancer therapy, cancer immunotherapy, vaccines, immunotherapy, mRNA vaccines
- Disciplines:Other veterinary sciences not elsewhere classified, Drug discovery and development not elsewhere classified, Biopharmaceuticals, Molecular medicine, Non-clinical studies, Vaccines, Animal health engineering, Laboratory animal medicine, Veterinary law and legislation, Veterinary herd health management, Agricultural, veterinary and food sciences not elsewhere classified, Veterinary medicine not elsewhere classified, Applied immunology, Cancer therapy, Gene and molecular therapy, Vaccinology, Veterinary immunology
Affiliations
- Department of Veterinary and Biosciences (Department)
Member
From1 Feb 2008 → Today - Department of Pharmaceutics (Department)
Member
From1 Oct 1997 → 30 Sep 2008
Projects
1 - 10 of 35
- Enhanced self-amplifying RNA with prolonged protein production and reduced side-effects.From1 Nov 2024 → TodayFunding: BOF - doctoral mandates
- Investigation of the potential of novel cationic polymers as non-viral carriers for RNA-based applicationsFrom1 Oct 2024 → TodayFunding: BOF - doctoral mandates
- Efficacy and immunological aspects of self-amplifying (sa) RNA vaccines encoding avian influenza antigensFrom15 Jun 2024 → TodayFunding: BOF - doctoral mandates
- Replacement of confocal fluorescence microscope for visualisation of biological processes in humans and animalsFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Novel cationic polymers for RNA vaccinationFrom15 Dec 2022 → TodayFunding: IOF - technology concept exploration
- Introducing mRNA vaccination in chicken: first steps towards a commercial mRNA vaccine against a leading viral infection in chickenFrom1 Nov 2022 → TodayFunding: IOF - technology validation in lab
- A self-amplifying mRNA-based combinatorial immunotherapy for treating colorectal cancerFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Development of a buccal self-amplifying mRNA vaccine for periodontal disease prophylaxis in dogs.From1 Nov 2021 → 30 Jun 2023Funding: FWO Strategic Basic Research Grant
- Biofabrication of vasculature for organ engineering and bypass graftingFrom1 Nov 2021 → TodayFunding: FWO fellowships
- BioGelator for local immunotherapyFrom15 Jul 2021 → TodayFunding: IOF - technology validation in lab
Publications
11 - 20 of 124
- Mucosal vaccination against periodontal disease : unexploited potential for veterinary and human oral medicine(2022)
Authors: Victor Vaernewyck, Maria Soltero-Rivera, Boaz Arzi, Niek Sanders, Eric Cox, Bert Devriendt
Pages: 21 - 26 - A dual-antigen self-amplifying RNA SARS-CoV-2 vaccine induces potent humoral and cellular immune responses and protects against SARS-CoV-2 variants through T cell-mediated immunity(2022)
Authors: Séan Mc Cafferty, A. K. M. Ashiqul Haque, Aster Vandierendonck, Brian Weidensee, Magalie Plovyt, Magdalena Stuchlikova, Nathalie François, Sophie Valembois, Leo Heyndrickx, Johan Michiels, et al.
Pages: 2968 - 2983 - Molecular therapies and vaccines face the challenges of emerging infectious diseases(2022)
Authors: Ami Patel, David Weiner, Weidong Xiao, Andrew Baker, Niek Sanders
Pages: 1789 - 1790 - A lipid nanoparticle platform for mRNA delivery through repurposing of cationic amphiphilic drugs(2022)
Authors: Bram Bogaert, Felix Sauvage, Roberta Guagliardo, Cristina Muntean, [missing] Van Phuc Nguyen, Eline Pottie, Mike Wels, An-Katrien Minnaert, Qiangbing Yang, Dan Peer, et al.
Pages: 256 - 270 - Sterilizing immunity against SARSU+2010CoVU+20102 infection in mice by a singleU+2010shot and lipid amphiphile imidazoquinoline TLR7/8 agonistU+2010adjuvanted recombinant spike protein vaccine**(2021)
Authors: Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn, Simon Van Herck, Lutz Nuhn, Kim Deswarte, Niek Sanders, et al.
Pages: 9467 - 9473 - Mucosal vaccination against periodontal disease : current status and opportunities(2021)
Authors: Victor Vaernewyck, Boaz Arzi, Niek Sanders, Eric Cox, Bert Devriendt
- Corticosteroids and cellulose purification improve, respectively, the in vivo translation and vaccination efficacy of sa-mRNAs(2021)
Authors: Séan Mc Cafferty, Lisa Opsomer, Haixiu Wang, Hanne Huysmans, Joyca De Temmerman, Stefan Lienenklaus, Francis Combes, Niek Sanders
Pages: 1370 - 1381 - OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer(2021)
Authors: Jonas Steenbrugge, Niek Sanders, Eric Ciamporcero, Timothy Perera
- Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across(2021)
Authors: An-Katrien Minnaert, Helena Vanluchene, Rein Verbeke, Ine Lentacker, Koen Raemdonck, Niek Sanders, Katrien Remaut
- Low-dose single-shot COVID-19 mRNA vaccines lie ahead(2021)
Authors: Niek Sanders
Pages: 1944 - 1945