Researcher
Rein Verbeke
- Disciplines:Other pharmaceutical sciences, Pharmacognosy, Pharmogenetics and -genomics, Pharmacotherapy, Biomarker discovery, Clinical trials, Toxicogenomics, Biopharmaceuticals, Biopharmaceutics
Affiliations
- Department of Pharmaceutics (Department)
Member
From16 Sep 2013 → Today
Projects
1 - 4 of 4
- LNP-DECODE: Deciphering the adjuvants activity of lipid nanoparticle-based mRNA vaccines in primary dendritic cellsFrom1 Jan 2024 → TodayFunding: BOF - projects
- Exploration of an mRNA based nanovaccine platform and immunopeptidomics for the development of more effective tuberculosis vaccines.From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Understanding and modulating the pro-inflammatory activity of lipid nanoparticles (LNP) in the COVID-19 mRNA vaccines: towards the development of more effective LNP formulations.From1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- mRNA Lipid nanoparticles co-loaded with alpha-Galactosylceramide as a universal influenza vaccine platformFrom1 Oct 2020 → 30 Sep 2022Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 27
- Continuous freeze-drying of messenger RNA lipid nanoparticles enables storage at higher temperatures(2023)
Authors: Sofie Meulewaeter, Gust Nuytten, Miffy H.Y. Cheng, Pieter R. Cullis, Thomas De Beer, Ine Lentacker, Rein Verbeke
Pages: 149 - 160 - Nanobody-mediated SPECT/CT imaging reveals the spatiotemporal expression of programmed death-ligand 1 in response to a CD8+ T cell and iNKT cell activating mRNA vaccine(2023)
Authors: Thomas Ertveldt, Sofie Meulewaeter, Yannick De Vlaeminck, Oscar Olarte, Katrijn Broos, Serge Van Calenbergh, Stephanie Bourgeois, Joke Deprez, Yves Heremans, Cleo Goyvaerts, et al.
Pages: 5483 - 5500 - Transport by circulating myeloid cells drives liposomal accumulation in inflamed synovium(2023)
Authors: Joke Deprez, Rein Verbeke, Sofie Meulewaeter, Ilke Aernout, Heleen Dewitte, Tine Decruy, Julie Coudenys, Julie Van Duyse, Gert Van Isterdael, Dan Peer, et al.
Pages: 1341 - 1350 - Innate immune mechanisms of mRNA vaccines(2022)
Authors: Rein Verbeke, Michael J. Hogan, Karin Loré, Norbert Pardi
Pages: 1993 - 2005 - Fluorine MR imaging probes dynamic migratory profiles of perfluorocarbon-loaded dendritic cells after streptozotocin-induced inflammation(2022)
Authors: Shweta Saini, An-Sofie Vanherwegen, Sayuan Liang, Rein Verbeke, Hannelie Korf, Ine Lentacker, Conny Gysemans, Uwe Himmelreich
Pages: 321 - 332 - Exciting times for lipid nanoparticles : how Canadian discoveries are enabling gene therapies(2022)
Authors: Miffy H. Y. Cheng, Cedric A. Brimacombe, Rein Verbeke, Pieter R. Cullis
Pages: 1663 - 1668 - Immunopeptidomics-based design of mRNA vaccine formulations against Listeria monocytogenes(2022)
Authors: Rupert Mayer, Rein Verbeke, Caroline Asselman, Ilke Aernout, Adillah Gul, Denzel Eggermont, Katie Boucher, Fabien Henri Thery, Teresa Maia, Hans Demol, et al.
- The dawn of mRNA vaccines : the COVID-19 case(2021)
Authors: Rein Verbeke, Ine Lentacker, Heleen Dewitte
Pages: 511 - 520 - Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across(2021)
Authors: An-Katrien Minnaert, Helena Vanluchene, Rein Verbeke, Ine Lentacker, Koen Raemdonck, Niek Sanders, Katrien Remaut
- mRNA-lipid nanoparticle COVID-19 vaccines : structure and stability(2021)
Authors: Linde Schoenmaker, Dominik Witzigmann, Jayesh A. Kulkarni, Rein Verbeke, Gideon Kersten, Wim Jiskoot, Daan J. A. Crommelin
Patents
1 - 2 of 2