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Publication
Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across
Journal Contribution - Review Article
Journal: ADVANCED DRUG DELIVERY REVIEWS
ISSN: 1872-8294
Volume: 176
Publication year:2021
- DOI: https://doi.org/10.1016/j.addr.2021.113900
- Handle: http://hdl.handle.net/1854/LU-8739558
- WoS Id: 000707389400009
- VABB Id: c:vabb:517275
Accessibility:Open
Authors/publisher
- An-Katrien Minnaert (Author)
- Helena Vanluchene (Author)
- Rein Verbeke (Author)
- Sabine Lentacker (Author)
- Stefaan De Smedt (Author)
- Koen Raemdonck (Author)
- Niek Sanders (Author)
- Katrien Remaut (Author)
- An-Katrien Minnaert (Editor)
Research units
Projects
- Genetic therapy for EYS- and USH2A-associated retinal dystrophy ("GET-READY")From1 Jun 2021 → TodayFunding: FWO research project (including WEAVE projects)
- High intensity focused ultrasound and mRNA nanomedicines: a new strategy to induce and boost anti-tumor immunityFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- The barrier role of the vitreoretinal interface toward intravitreal
injected proteins, viruses and siRNA nanoparticles: ex vivo bovine
screening models and siRNA nanoparticle design.From1 Jan 2018 → 31 Mar 2022Funding: FWO Strategic Basic Research Grant
- Smart design nanoParticles to Activate immune Responses against Cancer (SPARC)From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Strengthening the Research Area of Delivery of Nucleic acid mimics (NAMS) into bacteria to fight the antibiotic crisisFrom1 Aug 2018 → 31 Jan 2022Funding: H2020-EU.4. - Spreading excellence and widening participation
- Proteomics-derived epitopes for dramatically improved anticancer and antibacterial vaccine developmentFrom1 Jan 2021 → TodayFunding: BOF - projects
- Barriers and carriers for non-viral delivery of mRNA to induce transient protein expression in the retina: the hurdles of the inner limiting membrane and innate immunity versus the potential of mRNA self-amplification.From1 Nov 2019 → 31 Oct 2023Funding: FWO fellowships