Researcher
Niek Sanders
- Keywords:drug delivery, immunology, gene therapy, cancer therapy, cancer immunotherapy, vaccines, immunotherapy, mRNA vaccines
- Disciplines:Other veterinary sciences not elsewhere classified, Drug discovery and development not elsewhere classified, Biopharmaceuticals, Molecular medicine, Non-clinical studies, Vaccines, Animal health engineering, Laboratory animal medicine, Veterinary law and legislation, Veterinary herd health management, Agricultural, veterinary and food sciences not elsewhere classified, Veterinary medicine not elsewhere classified, Applied immunology, Cancer therapy, Gene and molecular therapy, Vaccinology, Veterinary immunology
Affiliations
- Department of Veterinary and Biosciences (Department)
Member
From1 Feb 2008 → Today - Department of Pharmaceutics (Department)
Member
From1 Oct 1997 → 30 Sep 2008
Projects
1 - 10 of 33
- Efficacy and immunological aspects of self-amplifying (sa) RNA vaccines encoding avian influenza antigensFrom15 Jun 2024 → TodayFunding: BOF - doctoral mandates
- Replacement of confocal fluorescence microscope for visualisation of biological processes in humans and animalsFrom15 Dec 2022 → TodayFunding: BOF - scientific equipment program
- Novel cationic polymers for RNA vaccinationFrom15 Dec 2022 → TodayFunding: IOF - technology concept exploration
- Introducing mRNA vaccination in chicken: first steps towards a commercial mRNA vaccine against a leading viral infection in chickenFrom1 Nov 2022 → TodayFunding: IOF - technology validation in lab
- A self-amplifying mRNA-based combinatorial immunotherapy for treating colorectal cancerFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Development of a buccal self-amplifying mRNA vaccine for periodontal disease prophylaxis in dogs.From1 Nov 2021 → 30 Jun 2023Funding: FWO Strategic Basic Research Grant
- Biofabrication of vasculature for organ engineering and bypass graftingFrom1 Nov 2021 → TodayFunding: FWO fellowships
- BioGelator for local immunotherapyFrom15 Jul 2021 → TodayFunding: IOF - technology validation in lab
- High throughput automatization of cell and organoid based assays for cross-health valorization -Acronym: ACOBAFrom1 May 2021 → 30 Apr 2023Funding: IOF - technology validation in lab
- Design of a Chlamydia vaccineFrom1 Nov 2020 → TodayFunding: BOF - doctoral mandates
Publications
1 - 10 of 124
- Evaluation of a self-amplifying mRNA reporter vaccine in explant models of broiler chickens(2023)
Authors: Janne Snoeck, Koen Chiers, Ying Tam, Niek Sanders, An Garmyn
- Previous and current efforts to develop a mucosal vaccine against periodontal disease : are we close yet?(2023)
Authors: Victor Vaernewyck, Janne Snoeck, Eric Cox, Niek Sanders, Boaz Arzi, Maria Soltero-Rivera, Henriëtte Booij-Vrieling, Bert Devriendt
Pages: 191 - 193 - Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue(2023)
Authors: Zifu Zhong, Yong Chen, Kim Deswarte, Heleen Lauwers, Emily De Lombaerde, Xiaole Cui, Simon Van Herck, Tingting Ye, Mark Gontsarik, Stefan Lienenklaus, et al.
- The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function(2023)
Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, et al.
- Evaluation of potential administration routes of self-amplifying mRNA in chickens using a reporter vaccine(2023)
Authors: Janne Snoeck, Kristof Haems, Ying Tam, Niek Sanders, An Garmyn
Number of pages: 1 - Novel polymers as promising non-viral carriers for self-amplifying mRNA-based applications(2023)
Authors: Lisa Opsomer, Somdeb Jana, Ine Mertens, Richard Hoogenboom, Niek Sanders
Number of pages: 1 - Xenogeneic equine stem cells activate anti-tumor adaptive immunity in a 4T1-based intraductal mouse model for triple-negative breast cancer : proof-of-principle(2023)
Authors: Jonas Steenbrugge, Glenn Pauwelyn, Kristel Demeyere, Nausikaa Devriendt, Hilde De Rooster, Niek Sanders, Jan H. Spaas, Evelyne Meyer, Sina Naserian
- Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics(2022)
Authors: Marie Pauwels, Junhua Xie, Adam Ceroi, Sriram Balusu, Jonas Castelein, Elien Van Wonterghem, Griet Van Imschoot, Andrew Ward, Trevelyan R. Menheniott, Oskar Gustafsson, et al.
- One cisplatin dose provides durable stimulation of anti-tumor immunity and alleviates anti-PD-1 resistance in an intraductal model for triple-negative breast cancer(2022)
Authors: Jonas Steenbrugge, Julie Bellemans, Niels Vander Elst, Josephine De Vliegher, Timothy Perera, Ward De Spiegelaere, Niek Sanders
- Regulatory guidelines and preclinical tools to study the biodistribution of RNA therapeutics(2022)
Authors: Pieter Vervaeke, S.E. Borgos, Niek Sanders, F. Combes