Researcher
Simon Van Herck
- Keywords:STING, Nanomedicine, cancer immunotherapy, Checkpoint inhibition
- Disciplines:Applied immunology, Particle design and technology, Cancer therapy, Biopharmaceuticals, Nanochemistry
Affiliations
- Department of Pharmaceutics (Department)
Member
From24 Nov 2014 → Today
Projects
1 - 2 of 2
- Normalising tumour pH to bring the STING back in anti-tumour immunityFrom1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- PRECISION IMMUNE-ENGINEERING OF THE TUMOR MICROENVIRONMENTFrom1 Oct 2019 → 30 Sep 2021Funding: BOF - postdoctoral mandates
Publications
1 - 10 of 28
- Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue(2023)
Authors: Zifu Zhong, Yong Chen, Kim Deswarte, Heleen Lauwers, Emily De Lombaerde, Xiaole Cui, Simon Van Herck, Tingting Ye, Mark Gontsarik, Stefan Lienenklaus, et al.
- Smart hydrogels delivered by high pressure aerosolization can prevent peritoneal adhesions(2023)
Authors: Helena Braet, Peter-Paul Fransen, Yong Chen, Simon Van Herck, Remco Mariën, Valérie Vanhoorne, Wim Ceelen, Annemieke Madder, Steven Ballet, Richard Hoogenboom, et al.
Pages: 138 - 150 - In situ tumor vaccination with calcium‐linked degradable coacervate nanocomplex co‐delivering photosensitizer and TLR7/8 agonist to trigger effective anti‐tumor immune responses(2022)
Authors: Yutong Liu, Hui Li, Huajun Zhao, Yanyun Hao, Simon Van Herck, Zejun Xu, Guan Wang, Xiao Wang, Xinke Zhang, Xiaoyan Ge, et al.
- Sterilizing immunity against SARSU+2010CoVU+20102 infection in mice by a singleU+2010shot and lipid amphiphile imidazoquinoline TLR7/8 agonistU+2010adjuvanted recombinant spike protein vaccine**(2021)
Authors: Sonia Jangra, Jana De Vrieze, Angela Choi, Raveen Rathnasinghe, Gabriel Laghlali, Annemiek Uvyn, Simon Van Herck, Lutz Nuhn, Kim Deswarte, Niek Sanders, et al.
Pages: 9467 - 9473 - Lipid nature and alkyl length influence lymph node accumulation of lipid-polyethylene glycol amphiphiles(2021)
Authors: Jana De Vrieze, Antonio Pires da Silva Baptista, Lutz Nuhn, Simon Van Herck, Kim Deswarte, Haijun Yu, Bart Lambrecht, Bruno De Geest
- Lipid-polyglutamate nanoparticle vaccine platform(2021)
Authors: Dorien Van Lysebetten, Alessio Malfanti, Kim Deswarte, Kaloian Koynov, Bianka Golba, Tingting Ye, Sabah Kasmi, Alexander Lamoot, Yong Chen, Simon Van Herck, et al.
Pages: 6011 - 6022 - Potent and prolonged innate immune activation by enzyme-responsive imidazoquinoline TLR7/8 agonist prodrug vesicles(2020)
Authors: Bi Wang, Simon Van Herck, Yong Chen, Xiangyang Bai, Kim Deswarte, Niek Sanders, Stefan Lienenklaus, Hans W. Scheeren, Sunil A. David, Fabian Kiessling, et al.
Pages: 12133 - 12139 - Design of pH-degradable polymer-lipid amphiphiles using a ketal-functionalized RAFT chain transfer agent(2020)
Authors: Jana De Vrieze, Simon Van Herck, Lutz Nuhn, Bruno De Geest
- Imidazoquinoline-conjugated degradable coacervate conjugate for local cancer immunotherapy(2020)
Authors: Hui Li, Simon Van Herck, Yongjun Liu, Yanyun Hao, Xiaochu Ding, Lutz Nuhn, Francis Combes, Niek Sanders, Stefan Lienenklaus, Stefaan De Koker, et al.
Pages: 4993 - 5000 - Zebrafish embryos allow prediction of nanoparticle circulation times in mice and facilitate quantification of nanoparticle-cell interactions(2020)
Authors: Nils-Jorgen Knudsen Dal, Agnese Kocere, Jens Wohlmann, Simon Van Herck, Tobias A. Bauer, Julien Resseguier, Shahla Bagherifam, Hilde Hyldmo, Matthias Barz, Bruno De Geest, et al.