Researcher
Niek Sanders
- Keywords:drug delivery, immunology, gene therapy, cancer therapy, cancer immunotherapy, vaccines, immunotherapy, mRNA vaccines
- Disciplines:Other veterinary sciences not elsewhere classified, Drug discovery and development not elsewhere classified, Biopharmaceuticals, Molecular medicine, Non-clinical studies, Vaccines, Animal health engineering, Laboratory animal medicine, Veterinary law and legislation, Veterinary herd health management, Agricultural, veterinary and food sciences not elsewhere classified, Veterinary medicine not elsewhere classified, Applied immunology, Cancer therapy, Gene and molecular therapy, Vaccinology, Veterinary immunology
Affiliations
- Department of Veterinary and Biosciences (Department)
Member
From1 Feb 2008 → Today - Department of Pharmaceutics (Department)
Member
From1 Oct 1997 → 30 Sep 2008
Projects
21 - 30 of 33
- Evaluation of immunogenic properties of modified mRNA and self-replicating RNA based vaccines against cancerFrom1 Oct 2014 → 31 Mar 2015Funding: FWO Humanitarian research project Stand up against Cancer
- Targeted release of chemotherapeutic agents with ultrasound and microbubblesFrom1 Sep 2012 → 30 Jun 2013Funding: BOF - Doctoral projects
- Evaluation of highly immunogenic tumor cell vaccines in combination with regulatory T-cell depletionFrom1 Oct 2011 → 30 Sep 2016Funding: BOF - Doctoral projects
- West Nile Integrated Shield Project: Epidemiology, Diagnosis and Prevention of West Nile Virus in EuropeFrom1 Feb 2011 → 28 Feb 2015Funding: Health
- Evaluation of delivery systems for mRNA cancer vaccinesFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Chlamydia psittaci DNA vaccination and alternativesFrom1 Jan 2011 → 31 Dec 2016
- Doxorubicin-loaded microbubbles for ultrasound controlled destruction of tumor cellsFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Targeted delivery of PEGylated adeno-associated viral vectorsFrom1 Jan 2010 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- In vivo evaluation of non-viral mRNA delivery systems for mRNA vaccination against cancer.From1 Oct 2009 → 30 Sep 2014Funding: FWO fellowships, BOF - Other initiatives
- Sonodrugs-image-controlled ultrasound- induced drug deliveryFrom1 Nov 2008 → 31 Oct 2013Funding: Nanosciences, nanotechnologies, materials & new production technologies
Publications
1 - 10 of 124
- Evaluation of a self-amplifying mRNA reporter vaccine in explant models of broiler chickens(2023)
Authors: Janne Snoeck, Koen Chiers, Ying Tam, Niek Sanders, An Garmyn
- Previous and current efforts to develop a mucosal vaccine against periodontal disease : are we close yet?(2023)
Authors: Victor Vaernewyck, Janne Snoeck, Eric Cox, Niek Sanders, Boaz Arzi, Maria Soltero-Rivera, Henriëtte Booij-Vrieling, Bert Devriendt
Pages: 191 - 193 - Lipid nanoparticle delivery alters the adjuvanticity of the TLR9 agonist CpG by innate immune activation in lymphoid tissue(2023)
Authors: Zifu Zhong, Yong Chen, Kim Deswarte, Heleen Lauwers, Emily De Lombaerde, Xiaole Cui, Simon Van Herck, Tingting Ye, Mark Gontsarik, Stefan Lienenklaus, et al.
- The impact of hepatocyte-specific deletion of hypoxia-inducible factors on the development of polymicrobial sepsis with focus on GR and PPARα function(2023)
Authors: Tineke Vanderhaeghen, Steven Timmermans, Melanie Eggermont, Deepika Watts, Jolien Vandewalle, Charlotte Wallaeys, Louise Nuyttens, Joyca De Temmerman, Tino Hochepied, Sylviane Dewaele, et al.
- Evaluation of potential administration routes of self-amplifying mRNA in chickens using a reporter vaccine(2023)
Authors: Janne Snoeck, Kristof Haems, Ying Tam, Niek Sanders, An Garmyn
Number of pages: 1 - Novel polymers as promising non-viral carriers for self-amplifying mRNA-based applications(2023)
Authors: Lisa Opsomer, Somdeb Jana, Ine Mertens, Richard Hoogenboom, Niek Sanders
Number of pages: 1 - Xenogeneic equine stem cells activate anti-tumor adaptive immunity in a 4T1-based intraductal mouse model for triple-negative breast cancer : proof-of-principle(2023)
Authors: Jonas Steenbrugge, Glenn Pauwelyn, Kristel Demeyere, Nausikaa Devriendt, Hilde De Rooster, Niek Sanders, Jan H. Spaas, Evelyne Meyer, Sina Naserian
- Choroid plexus-derived extracellular vesicles exhibit brain targeting characteristics(2022)
Authors: Marie Pauwels, Junhua Xie, Adam Ceroi, Sriram Balusu, Jonas Castelein, Elien Van Wonterghem, Griet Van Imschoot, Andrew Ward, Trevelyan R. Menheniott, Oskar Gustafsson, et al.
- One cisplatin dose provides durable stimulation of anti-tumor immunity and alleviates anti-PD-1 resistance in an intraductal model for triple-negative breast cancer(2022)
Authors: Jonas Steenbrugge, Julie Bellemans, Niels Vander Elst, Josephine De Vliegher, Timothy Perera, Ward De Spiegelaere, Niek Sanders
- Regulatory guidelines and preclinical tools to study the biodistribution of RNA therapeutics(2022)
Authors: Pieter Vervaeke, S.E. Borgos, Niek Sanders, F. Combes