Researcher
Chris Ulens
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory of Structural Neurobiology (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Structural Neurobiology (Division)
Member
From1 Oct 2007 → Today - Toxicology and Pharmacology (Division)
Member
From1 Oct 1999 → 31 Jan 2004
Projects
1 - 10 of 30
- Structural and functional studies of ligand-activated insect ion channels for the development of safer insecticidesFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular mechanism of insect pentameric ligand-gated ion channels as a target for new insecticidesFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Structural and functional characterisation of the Myzus persicae nicotinic acetylcholine receptors for the development of safer agricultural pesticidesFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Development of nanobodies as a strategy to neutralize neurotoxins in envenomation by poisonous snakebites.From12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- A broad-spectrum antidote against venomous snakebites based on engineering of nicotinic acetylcholine receptors and derivatives.From1 Nov 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Molecular mechanism of the honeybee nicotinic acetylcholine receptor, the target for neonic insecticidesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- A 200 kV transmission electron microscope for high-resolution determination of 3D-ultrastructure of native proteins, cells and tissueFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO International research infrastructure (IRI)
- Development of a powerful antidote against lethal neurotoxic snakebites using the naturally occurring acetylcholine binding protein (AChBP) as a decoy receptor.From1 Oct 2019 → 30 Sep 2022Funding: IOF - technology validation in lab
Publications
41 - 50 of 60
- The Prokaryote Ligand-Gated Ion Channel Elic Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine(2014)
Authors: Chris Ulens, Radovan Spurny, Andrew J Thompson, Mona Alqazzaz, Sarah Debaveye, Han Lu, Kerry Price, Jose M Villalgordo, Gary Tresadern, Gary Tresadern, et al.
Pages: 342 - Biochemical and Functional Characterization of a Novel Prokaryote Ligand-Gated Ion Channel CLIC(2014)
Authors: Mieke Nys, Radovan Spurny, Zander Claes, Chris Ulens
Pages: 545 - Family of prokaryote cyclic nucleotide-modulated ion channels(2014)
Authors: Radovan Spurny, Chris Ulens
Pages: 7855 - 7860 - The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine(2014)
Authors: Chris Ulens, Radovan Spurny
Pages: 1399 - 1407 - Pharmacological Properties of Cinnamaldehyde on NaChBac(2014)
Authors: Divya Kesters, Jan Tytgat, Thomas Voets, Karel Talavera, Chris Ulens
Pages: 132 - A Family of HCN Channel Homologs in Bacteria(2014)
Authors: Jana Kusch, Marijke Brams, Chris Ulens
Pages: 760 - Affinity comparison of p3 and p8 peptide displaying bacteriophages using surface plasmon resonance(2013)
Authors: Karel Knez, Nick Geukens, Kris Janssen, Dragana Spasic, Kim Vriens, Karin Thevissen, Bruno Cammue, Chris Ulens, Hans Deckmyn, Jeroen Lammertyn
Pages: 10075 - 10082 - Multi-Site Binding Of A General Anesthetic To The Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC(2013)
Authors: Radovan Spurny, Bert Billen, Sergei Strelkov, Jan Tytgat, Chris Ulens
Pages: 8355 - 8364 - Structural insights into Cys-loop receptor function and ligand recognition(2013)
Authors: Mieke Nys, Divya Kesters, Chris Ulens
Pages: 1042 - 1053 - Structural basis of ligand recognition in 5-HT(3) receptors(2013)
Authors: Divya Kesters, Radovan Spurny, Chris Ulens
Pages: 49 - 56