Researcher
Nick Geukens
- Disciplines:Laboratory medicine, Medical biotechnology, Regenerative medicine, Other basic sciences, Other health sciences, Drug discovery and development, Pharmaceutics, Other medical and health sciences
Affiliations
- Therapeutic and Diagnostic Antibodies (Division)
Member
From15 May 2019 → Today - Chemistry, Kulak Kortrijk Campus (Department)
Member
From1 Sep 2009 → 14 May 2019 - Faculty of Science, Kulak Kortrijk Campus (Faculty)
Member
From14 Jul 2008 → 31 Aug 2009 - Laboratory of Molecular Bacteriology (Rega Institute) (Division)
Member
From1 Oct 1999 → 13 Jul 2008
Projects
1 - 10 of 23
- Next generation immunotherapy solutions against macrophages to overcome cancer immuno-resistanceFrom1 Mar 2024 → TodayFunding: IOF - technology validation in lab
- A novel targeted therapy to treat bleeding in patients with a left ventricular assist device.From1 May 2023 → TodayFunding: IOF - mandates
- Flow cytometer for the Interdisciplinary Research Facility Life Sciences at Campus Kulak KortrijkFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Next-generation DNA vectors to improve efficacy, precision and accessibility of antibody gene transferFrom15 Mar 2022 → 14 Mar 2024Funding: BOF - various
- Targeted mass spectrometry-based quantification of autoantibodies in systemic rheumatic diseasesFrom1 Oct 2021 → 30 Sep 2023Funding: FWO Applied Biomedical Research (TBM)
- Rational design of biologics for therapeutic development (FoldCo)From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research (SBO)
- Why dose lung damage sometimes continue to worsen after the body seems to have cleared the SARS-CoV-2 virus?From1 Oct 2021 → 31 Mar 2023Funding: Foreign private sponsor - undefined
- Unraveling of protective innate and adaptive immune responses to SARS-CoV-2 in the setting of HCoV crossreactivityFrom1 Jan 2021 → 31 Dec 2022Funding: IOF - technology validation in lab
- VyCAP single cell isolation platform for high-quality single-cell analysisFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
Publications
1 - 10 of 65
- Exploring the Fate of Antibody-Encoding pDNA after Intramuscular Electroporation in Mice(2023)
Authors: Marie-Lynn Cuypers, Nick Geukens, Paul Declerck, Maarten Dewilde
- Antinuclear antibodies in individuals with COVID-19 reflect underlying disease: Identification of new autoantibodies in systemic sclerosis (CDK9) and malignancy (RNF20, RCC1, TRIP13)(2023)
Authors: Xavier Bossuyt, Glynis Frans, Nick Geukens, Sebastien Carpentier, Sabine Tejpar, Hans Wildiers, Daniel Engelbert Blockmans, Ellen De Langhe, Pieter Vermeersch, Rita Derua
- FLUIDOT: a Modular Microfluidic Platform for Single-Cell Study and Retrieval, with Applications in Drug Tolerance Screening and Antibody Mining(2023)
Authors: Jolien Breukers, Karen Ven, Iene Rutten, Maya Imbrechts, Julie Van Lent, Winnie Kerstens, Sam Noppen, Dominique Schols, Hendrik Jan Thibaut, Karen Vanhoorelbeke, et al.
- Complementarity determining regions in SARS-CoV-2 hybrid immunity(2023)
Authors: Glynis Frans, Jonas De Leeuw, Wim Maes, Bas Calcoen, Nick Geukens, Rita Derua, Pieter Vermeersch, Sebastien Carpentier, Xavier Bossuyt
- Detection of Breast Cancer-Specific Extracellular Vesicles with Fiber-Optic SPR Biosensor(2023)
Authors: Yagmur Yildizhan, Debby Thomas, Nick Geukens, Jeroen Lammertyn, Dragana Spasic
- Bivalent intra-spike binding provides durability against emergent Omicron lineages Results from a global consortium(2023)
Authors: Nick Geukens, Maya Imbrechts
- Clinically relevant dosing and pharmacokinetics of DNA-encoded antibody therapeutics in a sheep model(2022)
Authors: Debby Thomas, Maarten Dewilde, Nick Geukens, Paul Declerck
- Potent neutralizing anti-SARS-CoV-2 human antibodies cure infection with SARS-CoV-2 variants in hamster model(2022)
Authors: Maya Imbrechts, Wim Maes, Louanne Ampofo, Nathalie Van den Berghe, Bas Calcoen, Winnie Kerstens, Madina Rasulova, Sam Noppen, Rana Abdelnabi, Piet Maes, et al.
- Next generation point-of-care test for therapeutic drug monitoring of adalimumab in patients diagnosed with autoimmune diseases(2022)
Authors: Henry Ordutowski, Francesco Dal Dosso, Wout De Wispelaere, Charlotte Van Tricht, Séverine Vermeire, Nick Geukens, Dragana Spasic, Jeroen Lammertyn
- Intratumoral DNA-based delivery of checkpoint-inhibiting antibodies and interleukin 12 triggers T cell infiltration and anti-tumor response(2022)
Authors: Liesl Jacobs, Lidia Yshii, Steffie Junius, Nick Geukens, Adrian Liston, Paul Declerck
Pages: 984 - 992
Patents
1 - 5 of 5
- Screening and sorting of single cells (Inventor)
- Dual targeting of tafi and pai-1 (Inventor)
- Screening and sorting of single cells (Inventor)
- Dual targeting of tafi and pai-1 (Inventor)
- Dual targeting of tafi and pai-1 (Inventor)
Linked dataset
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