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Researcher
Chris Ulens
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory of Structural Neurobiology (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Structural Neurobiology (Division)
Member
From1 Oct 2007 → Today - Toxicology and Pharmacology (Division)
Member
From1 Oct 1999 → 31 Jan 2004
Projects
1 - 10 of 30
- Structural and functional studies of ligand-activated insect ion channels for the development of safer insecticidesFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular mechanism of insect pentameric ligand-gated ion channels as a target for new insecticidesFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Structural and functional characterisation of the Myzus persicae nicotinic acetylcholine receptors for the development of safer agricultural pesticidesFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Development of nanobodies as a strategy to neutralize neurotoxins in envenomation by poisonous snakebites.From12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- A broad-spectrum antidote against venomous snakebites based on engineering of nicotinic acetylcholine receptors and derivatives.From1 Nov 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Molecular mechanism of the honeybee nicotinic acetylcholine receptor, the target for neonic insecticidesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- A 200 kV transmission electron microscope for high-resolution determination of 3D-ultrastructure of native proteins, cells and tissueFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO International research infrastructure (IRI)
- Development of a powerful antidote against lethal neurotoxic snakebites using the naturally occurring acetylcholine binding protein (AChBP) as a decoy receptor.From1 Oct 2019 → 30 Sep 2022Funding: IOF - technology validation in lab
Publications
1 - 10 of 60
- Acetylcholine-Binding Protein Affinity Profiling of Neurotoxins in Snake Venoms with Parallel Toxin Identification(2023)
Authors: Chris Ulens
- An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules(2023)
Authors: Mieke Nys, Chris Ulens
- Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor(2023)
Authors: Casey Gallagher, Chris Ulens
- High-Throughput Venomics(2023)
Authors: Chris Ulens
Pages: 1734 - 1746 - Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium(2022)
Authors: Chris Ulens
- The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors(2022)
Authors: Mieke Nys, Chris Ulens
- Spicy Science: Structural snapshots of a polymodal nociceptor reveal insights on our sensation to pain, heat, and taste(2022)
Authors: Chris Ulens
- Clinical and molecular characteristics of a novel rare de novo variant in PPP2CA in a patient with a developmental disorder, autism, and epilepsy.(2022)
Authors: Iris Verbinnen, Chris Ulens, Veerle Janssens
- Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site(2021)
Authors: Chris Ulens
- The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels(2020)
Authors: Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Tassos Economou, Frederic Rousseau, Joost Schymkowitz, Chris Ulens
Pages: 29090 - 29100