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Researcher
Chris Ulens
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory of Structural Neurobiology (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Structural Neurobiology (Division)
Member
From1 Oct 2007 → Today - Toxicology and Pharmacology (Division)
Member
From1 Oct 1999 → 31 Jan 2004
Projects
11 - 20 of 30
- 3-dimensional structure and function of SthK, a prokaryote cyclic nucleotide-gated ion channel.From1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Pentameric ion channels as targets for drug discovery in human diseaseFrom1 Sep 2018 → 27 Sep 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Structure-based discovery of positive allosteric modulators of the alpha7 nicotinic ecetylcholine receptor as cognition enhancers.From2 Jul 2018 → 31 May 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- 3-dimensional structure and function of a cyclic nucleotide-gated ion channelFrom1 Oct 2017 → 30 Sep 2021Funding: Fund Recuperation Fiscal Exemption, BOF - Concerted Research Project from 1994
- 3-dimensional structure and function of a TRPM ion channelFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- 3D-structure and function of a TRPM ion channelFrom1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
- Upgrade and capacity increase to the Macromolecular Crystallization FacilityFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Structure-based discovery of positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor as cognition enhancers.From1 Oct 2016 → 30 Sep 2018Funding: IOF - Industrial Research Fund
- High throughput analysis of biomolecular interactionsFrom1 May 2016 → 30 Apr 2020Funding: FWO Medium Size Research Infrastructure
- A structural study of pentameric ligand-gated ion channels.From1 Oct 2013 → 30 Sep 2017Funding: BOF - Concerted Research Project from 1994
Publications
1 - 10 of 60
- Acetylcholine-Binding Protein Affinity Profiling of Neurotoxins in Snake Venoms with Parallel Toxin Identification(2023)
Authors: Chris Ulens
- An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules(2023)
Authors: Mieke Nys, Chris Ulens
- Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor(2023)
Authors: Casey Gallagher, Chris Ulens
- High-Throughput Venomics(2023)
Authors: Chris Ulens
Pages: 1734 - 1746 - Probing effects of the SARS-CoV-2 E protein on membrane curvature and intracellular calcium(2022)
Authors: Chris Ulens
- The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors(2022)
Authors: Mieke Nys, Chris Ulens
- Spicy Science: Structural snapshots of a polymodal nociceptor reveal insights on our sensation to pain, heat, and taste(2022)
Authors: Chris Ulens
- Clinical and molecular characteristics of a novel rare de novo variant in PPP2CA in a patient with a developmental disorder, autism, and epilepsy.(2022)
Authors: Iris Verbinnen, Chris Ulens, Veerle Janssens
- Regulation of a pentameric ligand-gated ion channel by a semiconserved cationic lipid-binding site(2021)
Authors: Chris Ulens
- The structural basis for an on-off switch controlling Gβγ-mediated inhibition of TRPM3 channels(2020)
Authors: Mieke Nys, Nikolaos Louros, Rodrigo Gallardo, Valentina Zorzini, Tassos Economou, Frederic Rousseau, Joost Schymkowitz, Chris Ulens
Pages: 29090 - 29100