Researcher
Chris Ulens
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory of Structural Neurobiology (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Structural Neurobiology (Division)
Member
From1 Oct 2007 → Today - Toxicology and Pharmacology (Division)
Member
From1 Oct 1999 → 31 Jan 2004
Projects
1 - 10 of 30
- Structural and functional studies of ligand-activated insect ion channels for the development of safer insecticidesFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular mechanism of insect pentameric ligand-gated ion channels as a target for new insecticidesFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Structural and functional characterisation of the Myzus persicae nicotinic acetylcholine receptors for the development of safer agricultural pesticidesFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Development of nanobodies as a strategy to neutralize neurotoxins in envenomation by poisonous snakebites.From12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- A broad-spectrum antidote against venomous snakebites based on engineering of nicotinic acetylcholine receptors and derivatives.From1 Nov 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Molecular mechanism of the honeybee nicotinic acetylcholine receptor, the target for neonic insecticidesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- A 200 kV transmission electron microscope for high-resolution determination of 3D-ultrastructure of native proteins, cells and tissueFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO International research infrastructure (IRI)
- Development of a powerful antidote against lethal neurotoxic snakebites using the naturally occurring acetylcholine binding protein (AChBP) as a decoy receptor.From1 Oct 2019 → 30 Sep 2022Funding: IOF - technology validation in lab
Publications
11 - 20 of 60
- Editorial: From Peptide and Protein Toxins to Ion Channel Structure/Function and Drug Design(2020)
Authors: Chris Ulens
- Thermodynamic and Evolutionary Coupling between the Native and Amyloid State of Globular Proteins(2020)
Authors: Rodrigo Gallardo, Rob van der Kant, Nikolaos Louros, Emiel Michiels, Bert Houben, Chris Ulens, Frederic Rousseau, Joost Schymkowitz
- A Lipid Recognition Site at a Transmembrane Helix Kink Shapes the Agonist Response of a Pentameric Ligand-gated Ion Channel(2020)
Authors: John E Baenziger, Camille M Henault, Cedric Govaerts, Argel Estrada, Joseph Lynch, Daniel Bertrand, Els Pardons, Genevieve Evans, Kristen N Woods, Benjamin W Elberson, et al.
Pages: 191A - 191A - Molecular Recognition of Neonicotinoid Insecticides by Honeybee Nicotinic Receptors and ACHBP Homologues(2020)
Authors: Chris Ulens, Quinty Bisseling, Marijke Brams, Aujan Mehregan, Genevieve Evans, Diletta Pasini, Hester Beard, Steven Verhelst, Alexander Fish, Sofie van Dorst, et al.
Pages: 585A - 585A - Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT3 receptor via a common vestibule site(2020)
Authors: Genevieve Evans, Chris Ulens
- A lipid site shapes the agonist response of a pentameric ligand-gated ion channel(2019)
Authors: Genevieve Evans, Chris Ulens
Pages: 1156 - + - A Decoy-Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite(2019)
Authors: Chris Ulens
- Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1(2019)
Authors: Mieke Nys, Rita Derua, Monique Beullens, Chris Ulens, Luc Van Meervelt, Mathieu Bollen
Pages: 507 - + - Structure of a transporter domain emerges(2018)
Authors: Chris Ulens
Pages: 20008 - 20009 - Mutations in the voltage-sensing domain affect the alternative ion permeation pathway in the TRPM3 channel(2018)
Authors: Kathi Held, Fabian Gruss, Davide Aloi, Annelies Janssens, Chris Ulens, Thomas Voets, Joris Vriens
Pages: 2413 - 2432