Researcher
Chris Ulens
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing
Affiliations
- Laboratory of Structural Neurobiology (Division)
Responsible
From1 Jan 2012 → Today - Laboratory of Structural Neurobiology (Division)
Member
From1 Oct 2007 → Today - Toxicology and Pharmacology (Division)
Member
From1 Oct 1999 → 31 Jan 2004
Projects
1 - 10 of 30
- Structural and functional studies of ligand-activated insect ion channels for the development of safer insecticidesFrom1 Oct 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Molecular mechanism of insect pentameric ligand-gated ion channels as a target for new insecticidesFrom1 Oct 2023 → TodayFunding: Fund Recuperation Fiscal Exemption, BOF - projects
- Structural and functional characterisation of the Myzus persicae nicotinic acetylcholine receptors for the development of safer agricultural pesticidesFrom1 Oct 2023 → TodayFunding: FWO junior postdoctoral fellowship
- Development of nanobodies as a strategy to neutralize neurotoxins in envenomation by poisonous snakebites.From12 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- When size matters: a platform to study molecular interactions and multimerisationFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- A broad-spectrum antidote against venomous snakebites based on engineering of nicotinic acetylcholine receptors and derivatives.From1 Nov 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Molecular mechanism of the honeybee nicotinic acetylcholine receptor, the target for neonic insecticidesFrom1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- A 200 kV transmission electron microscope for high-resolution determination of 3D-ultrastructure of native proteins, cells and tissueFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO International research infrastructure (IRI)
- Development of a powerful antidote against lethal neurotoxic snakebites using the naturally occurring acetylcholine binding protein (AChBP) as a decoy receptor.From1 Oct 2019 → 30 Sep 2022Funding: IOF - technology validation in lab
Publications
31 - 40 of 60
- The Crystal Structure of ELIC in Complex with Chlorpromazine Unexpectedly Unveils an Allosteric Binding Site in the Ligand-Binding Domain(2016)
Authors: Mieke Nys, Ana Farinha, Eveline Wijckmans, Marijke Brams, Ozge Yoluk, Magnus Andersson, Erik Lindahl, Chris Ulens
Pages: 457 - Novel mechanism of modulation at a ligand-gated ion channel; action of 5-Cl-indole at the 5-HT(3)A receptor(2016)
Authors: Chris Ulens
Pages: 3467 - 3479 - Functional and Biochemical Characterization of Alvinella Pompejana Cys-Loop Receptor Homologues(2016)
Authors: Eveline Wijckmans, Mieke Nys, Sarah Debaveye, Marijke Brams, Els Pardon, Daniel Bertrand, Jan Steyaert, Chris Ulens
Pages: 602 - Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBP(2015)
Authors: Chris Ulens
Pages: 1151 - 7 - Varenicline Interactions at the 5-HT3 Receptor Ligand Binding Site are Revealed by 5-HTBP(2015)
Authors: Kerry L Price, Reidun K Lillestol, Chris Ulens, Sarah C R Lummis
Pages: 1151 - 7 - Different Ligands of the TRPV3 Cation Channel Cause Distinct Conformational Changes As Revealed by Intrinsic Tryptophan Fluorescence Quenching(2015)
Authors: Bert Billen, Yeranddy Aguiar Alpizar, Etienne Waelkens, Karel Talavera Pérez, Bernd Nilius, Thomas Voets, Chris Ulens
Pages: 12964 - 74 - Molecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the alpha 7 nicotinic acetylcholine receptor(2015)
Authors: Radovan Spurny, Chris Ulens
Pages: E2543 - E2552 - Structure of the SthK Carboxy-Terminal Region Reveals a Gating Mechanism for Cyclic Nucleotide-Modulated Ion Channels(2015)
Authors: Divya Kesters, Mieke Nys, Eveline Wijckmans, Radovan Spurny, Thomas Voets, Jan Tytgat, Chris Ulens
- Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms(2015)
Authors: Chris Ulens
Pages: 2336 - 2353 - A family of prokaryote cyclic-nucleotide modulated ion channels(2014)
Authors: J Kusch, Marijke Brams, Radovan Spurny, Chris Ulens
Pages: 144 - 144