Researcher
Zeger Debyser
- Disciplines:Other biological sciences, Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
Affiliations
- Molecular Virology and Gene Therapy (Division)
Member
From1 Jan 2013 → Today - Molecular Virology and Gene Therapy (Division)
Responsible
From1 Jan 2012 → Today - Faculty of Medicine (Faculty)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
1 - 10 of 67 results
- Role of the epigenetic reader LEDGF/p75 in health and diseaseFrom1 Oct 2021 → TodayFunding: BOF - projects
- Towards a functional cure of HIV infectionFrom9 Feb 2021 → 31 May 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Cystic fibrosis is not only an ion channel defect - investigation of the role of senescence in chronic inflammation as a novel therapeutic strategyFrom17 Dec 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- OrganID: Organ-derived complex 2D/3D cultures in human diseaseFrom1 Oct 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
- A gene editing strategy for refractory CFTR mutations causing cystic fibrosis.From3 Sep 2020 → TodayFunding: Other federal public and semi-governmental institutions
- Investigation of the SARS-CoV-2.From1 Sep 2020 → TodayFunding: Foreign Nonprofit organisations and equivalents
- Identification of novel host factors regulating L1 retrotranspositionFrom5 Aug 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- EngelsFrom3 Aug 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Crystallographic facility for target-based drug designFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Strategies against persistent HIV-1 reservoirs(SAPHIR)From1 Jan 2020 → TodayFunding: FWO Strategic Basic Research (SBO)
Publications
1 - 10 of 277 results
- GS-9822, a preclinical LEDGIN candidate, displays a block-and-lock phenotype in cell culture(2021)
Authors: Anne Bruggemans, Gerlinde Vansant, Mini Balakrishnan, Michael L Mitchell, Ruby Cai, Frauke Christ, Zeger Debyser
Number of pages: 17 - Role of Transportin-SR2 in HIV-1 Nuclear Import(2021)
Authors: Maryam Tabasi, Ivan Nombela, Julie Janssens, Adrien P Lahousse, Frauke Christ, Zeger Debyser
Number of pages: 16 - Towards a functional cure of HIV-1: insight in the chromatin landscape of the provirus(2021)
Authors: Julie Janssens, Anne Bruggemans, Frauke Christ, Zeger Debyser
Number of pages: 12 - Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival(2021)
Authors: Siska Van Belle, Sara El Ashkar, Katerina Cermakova, Filip Matthijssens, Steven Goossens, Alessandro Canella, Courtney H Hodges, Frauke Christ, Jan De Rijck, Pieter Van Vlierberghe, et al.
Number of pages: 18 - LEDGINs, Inhibitors of the Interaction Between HIV-1 Integrase and LEDGF/p75, Are Potent Antivirals with a Potential to Cure HIV Infection.(2021)
Authors: Zeger Debyser, Anne Bruggemans, Siska Van Belle, Julie Janssens, Frauke Christ
Pages: 97 - 114 - Molecular Mechanism of LEDGF/p75 Dimerization(2020)
Authors: Vanda Lux, Tine Brouns, Katerina Cermakova, Pavel Srb, Milan Fabry, Marcela Madlikova, Magdalena Horejsi, Zdenek Kukacka, Petr Novak, Michael Kugler, et al.
Pages: 1288 - +Number of pages: 19 - Y-box-binding protein 1 supports the early and late steps of HIV replication (vol 13, e0200080, 2018)(2020)
Authors: Caroline Weydert, Bart van Heertum, Lieve Dirix, Stephanie De Houwer, Flore De Wit, Jan Mast, Steven J Husson, Katrien Busschots, Renate Konig, Rik Gijsbers, et al.
Number of pages: 3 - Author Correction: Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing.(2020)
Authors: Giulia Maule, Antonio Casini, Claudia Montagna, Anabela Santo Ramalho Venâncio, Kris De Boeck, Zeger Debyser, Marianne Carlon, Gianluca Petris, Anna Cereseto
Pages: 5457 - Imaging the Replication of Single Viruses: Lessons Learned from HIV and Future Challenges To Overcome(2020)
Authors: Susana Rocha, Jelle Hendrix, Doortje Borrenberghs, Zeger Debyser, Johan Hofkens
Pages: 10775 - 10783Number of pages: 9 - The chromatin landscape at the HIV-1 provirus integration site determines viral expression(2020)
Authors: Margareta Vansant, Heng-Chang Chen, Eduard Zorita, Katerina Trejbalova, Dalibor Miklik, Guillaume Filion, Zeger Debyser
Pages: 7801 - 7817Number of pages: 17