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Researcher
Zeger Debyser
- Disciplines:Laboratory medicine, Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering
Affiliations
- Molecular Virology and Gene Therapy (Division)
Responsible
From1 Jan 2012 → Today - Molecular Virology and Gene Therapy (Division)
Member
From1 Jan 2013 → Today - Faculty of Medicine, Kulak Kortrijk Campus (Faculty)
Member
From1 Oct 2003 → 29 Feb 2008 - Faculty of Medicine (Faculty)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
21 - 30 of 77
- Target validation and drug discovery towards a therapy for the Rett Syndrome.From1 Jan 2020 → 31 Dec 2023Funding: FWO research project (including WEAVE projects)
- ADVANCED ORGANOID ASSAYS FOR MODELLING HUMAN DISEASE – OrganADVANCEFrom14 Nov 2019 → TodayFunding: BOF - projects
- Target validation and drug discovery towards a treatment for Rett SyndromeFrom16 Oct 2019 → 16 Oct 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- single virus imaging of HIV infectionFrom23 Sep 2019 → 31 Aug 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting the chromatin-reader function of LEDGF/p75 for the treatment of Mixed-Lineage-Leukemia (TReaT-MLL)From1 Oct 2018 → 30 Sep 2020Funding: IOF - Industrial Research Fund
- The role of the MeCP2 binding partner LEGDF in the Rett syndrome and MECP2 duplication syndrome.From24 Sep 2018 → 30 Sep 2023Funding: FWO fellowships
- Development of an LEDGF/p75 based strategy for the treatment of MLL-rearranged leukemia.From1 Jan 2018 → 31 Dec 2021Funding: FWO research project (including WEAVE projects)
- Genome editing strategies to restore altered splicing eventsFrom9 Oct 2017 → 16 Jul 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Single virus imaging of early steps of HIV replicationFrom1 Oct 2017 → 30 Sep 2021Funding: BOF - Concerted Research Project from 1994
- Development of a new therapeutic strategy for MLL-rearranged leukemiaFrom1 Jan 2017 → 31 Dec 2018Funding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 304
- The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function(2024)
Authors: Siska Van Belle, Zeger Debyser
- The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture(2023)
Authors: Anne Bruggemans, Zeger Debyser
- Particle-based phasor-FLIM-FRET resolves protein-protein interactions inside single viral particles(2023)
Authors: Quinten Coucke, Guillermo Solís Fernández, Johan Hofkens, Zeger Debyser, Jelle Hendrix
- Development of novel therapeutic strategies for rare CFTR mutations causing severe cystic fibrosis(2023)
Authors: Marjolein Ensinck, Zeger Debyser, Christiane De Boeck, Marianne Carlon
- Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV-Based Vectors and for a Cure for HIV-1 Infection(2023)
Authors: Eline Pellaers, Anayat Bhat, Frauke Christ, Zeger Debyser
- Development of a new therapeutic strategy for the treatment of MLL-rearranged acute leukemia(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Single-Cell Imaging Shows That the Transcriptional State of the HIV-1 Provirus and Its Reactivation Potential Depend on the Integration Site(2022)
Authors: Zeger Debyser
- Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Expansion microscopy allows high resolution single cell analysis of epigenetic readers(2022)
Authors: Boris Louis, Susana Neves Rocha, Thierry Voet, Zeger Debyser, Johan Hofkens
- Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids(2022)
Authors: Marjolein Ensinck, Senne Cuyx, Lieven Dupont, Frauke Christ, Zeger Debyser, François Vermeulen, Marianne Carlon
Patents
1 - 9 of 9
- Functional cure of retroviral infection (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)