< Back to previous page
Researcher
Zeger Debyser
- Disciplines:Laboratory medicine, Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering
Affiliations
- Molecular Virology and Gene Therapy (Division)
Responsible
From1 Jan 2012 → Today - Molecular Virology and Gene Therapy (Division)
Member
From1 Jan 2013 → Today - Faculty of Medicine, Kulak Kortrijk Campus (Faculty)
Member
From1 Oct 2003 → 29 Feb 2008 - Faculty of Medicine (Faculty)
Member
From1 Oct 1999 → 30 Sep 2003
Projects
31 - 40 of 77
- Development of a new therapeutic strategy for the treatment of MLL-rearranged acute leukemiaFrom1 Jan 2017 → 16 Nov 2022Funding: FWO Strategic Basic Research Grant
- Development of gene and drug based therapies to target rare mutations causing severe cystic fibrosis.From1 Jan 2017 → 26 Jan 2023Funding: FWO Strategic Basic Research Grant
- The impact of LEDGIN-mediated retargeting of HIV integration on reactivation of latent HIVFrom1 Oct 2016 → 30 Sep 2020Funding: FWO fellowships
- High throughput analysis of biomolecular interactionsFrom1 May 2016 → 30 Apr 2020Funding: FWO Medium Size Research Infrastructure
- Research on the mechanism of action of a new class antivirals, the LEDGINs, with a potential application for the functional cure of HIV infectionFrom8 Jan 2016 → 16 Jan 2020Funding: FWO Strategic Basic Research Grant
- Single virus analysis of inhibitors of early HIV replication using fluorescence-based methods.From1 Jan 2016 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Organoid platform for the development of innovative treatments for Cystic FibrosisFrom1 Oct 2015 → 30 Sep 2017Funding: IOF - Industrial Research Fund
- Development of integrated single virus technology to study the early replication steps of HIVFrom1 Jan 2015 → 3 Oct 2019Funding: FWO fellowships
- Targeting the chromatin for innovative cancer therapy.From1 Nov 2014 → 31 Oct 2018Funding: SBO (Strategic basic research)
- Structure and function of nucleoprotein complexes involved in retroviral integrationFrom1 Oct 2014 → 5 Jul 2019Funding: BOF - Doctoral projects
Publications
1 - 10 of 304
- The Impact of Lens Epithelium-Derived Growth Factor p75 Dimerization on Its Tethering Function(2024)
Authors: Siska Van Belle, Zeger Debyser
- The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture(2023)
Authors: Anne Bruggemans, Zeger Debyser
- Particle-based phasor-FLIM-FRET resolves protein-protein interactions inside single viral particles(2023)
Authors: Quinten Coucke, Guillermo Solís Fernández, Johan Hofkens, Zeger Debyser, Jelle Hendrix
- Development of novel therapeutic strategies for rare CFTR mutations causing severe cystic fibrosis(2023)
Authors: Marjolein Ensinck, Zeger Debyser, Christiane De Boeck, Marianne Carlon
- Determinants of Retroviral Integration and Implications for Gene Therapeutic MLV-Based Vectors and for a Cure for HIV-1 Infection(2023)
Authors: Eline Pellaers, Anayat Bhat, Frauke Christ, Zeger Debyser
- Development of a new therapeutic strategy for the treatment of MLL-rearranged acute leukemia(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Single-Cell Imaging Shows That the Transcriptional State of the HIV-1 Provirus and Its Reactivation Potential Depend on the Integration Site(2022)
Authors: Zeger Debyser
- Design, synthesis, in silico studies, and antiproliferative evaluations of novel indolin-2-one derivatives containing 3-hydroxy-4-pyridinone fragment(2022)
Authors: Siska Van Belle, Zeger Debyser, Frauke Christ
- Expansion microscopy allows high resolution single cell analysis of epigenetic readers(2022)
Authors: Boris Louis, Susana Neves Rocha, Thierry Voet, Zeger Debyser, Johan Hofkens
- Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids(2022)
Authors: Marjolein Ensinck, Senne Cuyx, Lieven Dupont, Frauke Christ, Zeger Debyser, François Vermeulen, Marianne Carlon
Patents
1 - 9 of 9
- Functional cure of retroviral infection (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Functional cure of retroviral infection (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)