Researcher
Marjolein Ensinck
- Disciplines:Microbiology, Systems biology, Biomaterials engineering, Biological system engineering, Biomechanical engineering, Other (bio)medical engineering, Environmental engineering and biotechnology, Industrial biotechnology, Other biotechnology, bio-engineering and biosystem engineering, Laboratory medicine
Affiliations
- Molecular Virology and Gene Therapy (Division)
Member
From22 Aug 2016 → Today
Projects
1 - 1 of 1
- Development of gene and drug based therapies to target rare mutations causing severe cystic fibrosis.From1 Jan 2017 → 26 Jan 2023Funding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 14
- Nanoblades allow high-level genome editing in murine and human organoids(2023)
Authors: Mattijs Bulcaen, Marjolein Ensinck, François Vermeulen, Susana Neves Rocha, Louise Medaer, Rik Gijsbers, Marianne Carlon
- Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor(2023)
Authors: Marjolein Ensinck, Anabela Santo Ramalho Venâncio, Marianne Carlon
Pages: 1647 - 1660 - Development of novel therapeutic strategies for rare CFTR mutations causing severe cystic fibrosis(2023)
Authors: Marjolein Ensinck, Zeger Debyser, Christiane De Boeck, Marianne Carlon
- Nanoblades allow high-level genome editing in organoids(2022)
Authors: Mattijs Bulcaen, Marjolein Ensinck, Louise Medaer, Rik Gijsbers, Marianne Carlon
Pages: A8 - A8 - Base editing strategy to repair the CFTR 2789+5G > A splicing mutation(2022)
Authors: Marjolein Ensinck, François Vermeulen, Marianne Carlon
Pages: A137 - A137 - Severity of the S1251N allele in cystic fibrosis is affected by the presence of the F508C variant in cis(2022)
Authors: Senne Cuyx, Kaline Arnauts, Marc Ferrante, Catherine Verfaillie, Marjolein Ensinck, Marianne Carlon, Mieke Boon, Marijke Proesmans, Lieven Dupont, Christiane De Boeck, et al.
Pages: 644 - 651 - One Size Does Not Fit All: The Past, Present and Future of Cystic Fibrosis Causal Therapies(2022)
Authors: Marjolein Ensinck, Marianne Carlon
- Novel CFTR modulator combinations maximise rescue of G85E and N1303K in rectal organoids(2022)
Authors: Marjolein Ensinck, Senne Cuyx, Lieven Dupont, Frauke Christ, Zeger Debyser, François Vermeulen, Marianne Carlon
- Base and prime editing as potential gene correction therapy for cystic fibrosis(2021)
Authors: Mattijs Bulcaen, Marjolein Ensinck, François Vermeulen, Rik Gijsbers, Zeger Debyser, Marianne Carlon
Pages: A71 - A71 - On the Corner of Models and Cure: Gene Editing in Cystic Fibrosis(2021)
Authors: Marjolein Ensinck, Marianne Carlon
Patents
1 - 2 of 2