Researcher
Ine Lentacker
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Biophysics not elsewhere classified, Environmental safety and health of nanotechnology, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, In vitro testing, Biopharmaceuticals, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Other physical sciences not elsewhere classified, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 12
- A platform for the fast development of thermostable lyophilized mRNA lipid nanoparticle (LNP) vaccinesFrom7 Feb 2024 → TodayFunding: Foreign private sponsor - undefined
- Exploring co-encapsulation of antihistamines and immune checkpoint siRNAs in lipid nanoparticles for cancer immunotherapy.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Nanoparticle formulations of toll-like receptor agonists and oxaliplatin for local intraperitoneal delivery to treat colorectal peritoneal metastasisFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Exploration of an mRNA based nanovaccine platform and immunopeptidomics for the development of more effective tuberculosis vaccines.From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Exploring and advancing mRNA lipid nanoparticles for the in situ generation of CAR-MsFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Understanding and modulating the pro-inflammatory activity of lipid nanoparticles (LNP) in the COVID-19 mRNA vaccines: towards the development of more effective LNP formulations.From1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Light for life: high contrast multimodal medical imaging using inorganic fluorophoresFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Seeing is believing: Unraveling inflammation processes in auto-immune diabetes with non-invasive imaging.From1 Jan 2014 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Evaluation of mRNA loaded microbubbles for untrasound guided cancer vaccinationFrom1 Jan 2013 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Doxorubicin-loaded microbubbles for ultrasound controlled destruction of tumor cellsFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
Publications
11 - 20 of 65
- Strategies for controlling the innate immune activity of conventional and self-amplifying mRNA therapeutics : getting the message across(2021)
Authors: An-Katrien Minnaert, Helena Vanluchene, Rein Verbeke, Ine Lentacker, Koen Raemdonck, Niek Sanders, Katrien Remaut
- Cytosolic delivery of gadolinium via photoporation enables improved in vivo magnetic resonance imaging of cancer cells(2021)
Authors: Aranit Harizaj, Benedicte Descamps, Christophe Mangodt, Stephan Stremersch, Arianna Stoppa, Lieve Balcaen, Toon Brans, Nausikaa Devriendt, Juan Fraire, Eduardo Bolea Fernandez, et al.
Pages: 4005 - 4018 - Nanoparticle-sensitized photoporation enables inflammasome activation studies in targeted single cells dagger(2021)
Authors: Aranit Harizaj, Filip Van Hauwermeiren, Stephan Stremersch, Herlinde De Keersmaecker, Toon Brans, Juan Fraire, Karolien Grauwen, Ine Lentacker, Mohamed Lamkanfi, Kevin Braeckmans
Pages: 6592 - 6604 - Photoporation with biodegradable polydopamine nanosensitizers enables safe and efficient delivery of mRNA in human T cells(2021)
Authors: Aranit Harizaj, Mike Wels, Laurens Raes, Stephan Stremersch, Glenn Goetgeluk, Toon Brans, Félix Sauvage, Ine Lentacker, Kevin Braeckmans
- Opening doors with ultrasound and microbubbles : beating biological barriers to promote drug delivery(2021)
Authors: Joke Deprez, G. Lajoinie, Yanou Engelen, Stefaan De Smedt, Ine Lentacker
Pages: 9 - 36 - mRNA in cancer immunotherapy : beyond a source of antigen(2021)
Authors: Lien Van Hoecke, Rein Verbeke, Heleen Dewitte, Ine Lentacker, Karim Vermaelen, Karine Breckpot, Sandra Van Lint
- mRNA encoding a bispecific single domain antibody construct protects against influenza A virus infection in mice(2020)
Authors: Lien Van Hoecke, Rein Verbeke, Dorien De Vlieger, Heleen Dewitte, Sharon Van Nevel, Claus Bachert, Ine Lentacker
Pages: 777 - 787 - Ultrasound-responsive cavitation nuclei for therapy and drug delivery(2020)
Authors: Klazina Kooiman, Silke Roovers, Simone A. G. Langeveld, Robert T. Kleven, Heleen Dewitte, Meaghan A. O'Reilly, Jean-Michel Escoffre, Ayache Bouakaz, Martin D. Verweij, Kullervo Hynynen, et al.
Pages: 1296 - 1325 - Three decades of messenger RNA vaccine development(2019)
Authors: Rein Verbeke, Ine Lentacker, Stefaan De Smedt, Heleen Dewitte
- Broadening the message : a nanovaccine co-loaded with messenger RNA and α-GalCer induces antitumor immunity through conventional and natural killer T cells(2019)
Authors: Rein Verbeke, Ine Lentacker, Karine Breckpot, Jonas Janssens, Serge Van Calenbergh, Stefaan De Smedt, Heleen Dewitte
Pages: 1655 - 1669
Patents
1 - 2 of 2