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Project

Doxorubicin-loaded microbubbles for ultrasound controlled destruction of tumor cells

This project evaluates the use of doxorubicin-loaded microbubbles (i.e.: ultrasound responsive gas bubbles) for the destruction of circulating tumor cells. A new type of microbubbles will be designed for this purpose. These microbubbles have a surface loaded with anti-N-Cadherin antibodies that will be used to specifically recognize the circulating metastasis.

Date:1 Jan 2011 →  31 Dec 2014
Keywords:ultrasound, microbubbles, metastasis, doxorubicin
Disciplines:Other pharmaceutical sciences, Pharmacotherapy, Medicinal products, Pharmaceutics, Biomarker discovery and evaluation, Pharmacognosy and phytochemistry, Toxicology and toxinology, Drug discovery and development, Pharmacology