Researcher
Ine Lentacker
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Biophysics not elsewhere classified, Environmental safety and health of nanotechnology, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, In vitro testing, Biopharmaceuticals, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Other physical sciences not elsewhere classified, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 12
- A platform for the fast development of thermostable lyophilized mRNA lipid nanoparticle (LNP) vaccinesFrom7 Feb 2024 → TodayFunding: Foreign private sponsor - undefined
- Exploring co-encapsulation of antihistamines and immune checkpoint siRNAs in lipid nanoparticles for cancer immunotherapy.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Nanoparticle formulations of toll-like receptor agonists and oxaliplatin for local intraperitoneal delivery to treat colorectal peritoneal metastasisFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Exploration of an mRNA based nanovaccine platform and immunopeptidomics for the development of more effective tuberculosis vaccines.From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Exploring and advancing mRNA lipid nanoparticles for the in situ generation of CAR-MsFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Understanding and modulating the pro-inflammatory activity of lipid nanoparticles (LNP) in the COVID-19 mRNA vaccines: towards the development of more effective LNP formulations.From1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Light for life: high contrast multimodal medical imaging using inorganic fluorophoresFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Seeing is believing: Unraveling inflammation processes in auto-immune diabetes with non-invasive imaging.From1 Jan 2014 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Evaluation of mRNA loaded microbubbles for untrasound guided cancer vaccinationFrom1 Jan 2013 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Doxorubicin-loaded microbubbles for ultrasound controlled destruction of tumor cellsFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
Publications
31 - 40 of 65
- Tri-modal in vivo imaging of pancreatic islets transplanted subcutaneously in mice(2018)
Authors: Sayuan Liang, Karim Louchami, Bryan Holvoet, Rein Verbeke, Christophe M Deroose, Bella Manshian, Stefaan J Soenen, Ine Lentacker, Uwe Himmelreich
Pages: 940 - 951 - mRNA-based nanoparticles for therapeutic cancer vaccination(2017)
Authors: Rein Verbeke, Laura Wayteck, Karine Breckpot, Christian Vanhove, Benedicte Descamps, Heleen Dewitte, Ine Lentacker
Number of pages: 1 - Dynamic fluorescence microscopy of cellular uptake of intercalating model drugs by ultrasound-activated microbubbles(2017)
Authors: BHA Lammertink, R Deckers, M Derieppe, Ine De Cock, Ine Lentacker, G Storm, CTW Moonen, C Bos
Pages: 683 - 693 - Co-delivery of nucleoside-modified mRNA and TLR agonists for cancer immunotherapy : restoring the immunogenicity of immunosilent mRNA(2017)
Authors: Rein Verbeke, Ine Lentacker, Laura Wayteck, Karine Breckpot, Mieke Van Bockstal, Benedicte Descamps, Christian Vanhove, Heleen Dewitte
Pages: 287 - 300 - Sonoprinting and the importance of microbubble loading for the ultrasound mediated cellular delivery of nanoparticles(2016)
Authors: Ine De Cock, Guillaume Lajoinie, Michel Versluis, Ine Lentacker
Pages: 294 - 307 - Particle-mediated intravenous delivery of antigen mRNA results in strong antigen-specific T-cell responses despite the induction of type I interferon(2016)
Authors: Katrijn Broos, Kevin Vanderjeught, Janik Puttemans, Cleo Goyvaerts, Carlo Heirman, Heleen Dewitte, Rein Verbeke, Ine Lentacker, Kris Thielemans, Karine Breckpot
- In vitro methods to study bubble-cell interactions : fundamentals and therapeutic applications(2016)
Authors: Guillaume Lajoinie, Ine De Cock, Constantin C Coussios, Ine Lentacker, Séverine Le Gac, Eleanor Stride, Michel Versluis
- Laser-induced vapor nanobubbles for efficient delivery of macromolecules in live cells(2015)Volume: 9338
Authors: Ranhua Xiong, Koen Raemdonck, Karen Peynshaert, Ine Lentacker, Ine De Cock, Andre Skirtach, Kevin Braeckmans, WJ Parak, M Osinski, XJ Liang
Number of pages: 1 - Theranostic mRNA-loaded microbubbles in the lymphatics of dogs: implications for drug delivery(2015)
Authors: Heleen Dewitte, Katrien Vanderperren, Hendrik Haers, Emmelie Stock, Ine Lentacker
Pages: 97 - 109 - Ultrasound and microbubble mediated drug delivery: acoustic pressure as determinant for uptake via membrane pores or endocytosis(2015)
Authors: Ine De Cock, Elisa Zagato, Kevin Braeckmans, Ying Luan, Nico de Jong, Ine Lentacker
Pages: 20 - 28
Patents
1 - 2 of 2