Researcher
Ine Lentacker
- Disciplines:Nanobiotechnology, Nanoscale characterisation, Biophysics not elsewhere classified, Environmental safety and health of nanotechnology, Nanotechnology not elsewhere classified, Nanophotonics, Nanometrology, Drug discovery and development not elsewhere classified, Clinical trials, Compound screening, Other pharmaceutical sciences not elsewhere classified, In vitro testing, Biopharmaceuticals, Non-clinical studies, Vaccines, Nanomaterials, Nanomanufacturing, Nanofabrication, growth and self assembly, Other physical sciences not elsewhere classified, Nanoelectromechanical systems
Affiliations
- Department of Pharmaceutics (Department)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 12
- A platform for the fast development of thermostable lyophilized mRNA lipid nanoparticle (LNP) vaccinesFrom7 Feb 2024 → TodayFunding: Foreign private sponsor - undefined
- Exploring co-encapsulation of antihistamines and immune checkpoint siRNAs in lipid nanoparticles for cancer immunotherapy.From1 Oct 2023 → TodayFunding: BOF - doctoral mandates
- Nanoparticle formulations of toll-like receptor agonists and oxaliplatin for local intraperitoneal delivery to treat colorectal peritoneal metastasisFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Exploration of an mRNA based nanovaccine platform and immunopeptidomics for the development of more effective tuberculosis vaccines.From1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Exploring and advancing mRNA lipid nanoparticles for the in situ generation of CAR-MsFrom1 Nov 2022 → TodayFunding: FWO Strategic Basic Research Grant
- Understanding and modulating the pro-inflammatory activity of lipid nanoparticles (LNP) in the COVID-19 mRNA vaccines: towards the development of more effective LNP formulations.From1 Oct 2022 → TodayFunding: FWO senior postdoctoral fellowship
- Light for life: high contrast multimodal medical imaging using inorganic fluorophoresFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- Seeing is believing: Unraveling inflammation processes in auto-immune diabetes with non-invasive imaging.From1 Jan 2014 → 31 Dec 2019Funding: FWO research project (including WEAVE projects)
- Evaluation of mRNA loaded microbubbles for untrasound guided cancer vaccinationFrom1 Jan 2013 → 31 Dec 2018Funding: FWO research project (including WEAVE projects)
- Doxorubicin-loaded microbubbles for ultrasound controlled destruction of tumor cellsFrom1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
Publications
41 - 50 of 65
- Microbubbles as magic bullets in cancer immunotherapy(2015)
Authors: Heleen Dewitte, Katrien Vanderperren, Hendrik Haers, Emmelie Stock, Karine Breckpot, Ine Lentacker
Pages: 34 - 36 - Immunogenic mRNA nanoparticles for dendritic cell-based cancer vaccination(2015)
Authors: Rein Verbeke, Heleen Dewitte, Ine Lentacker
Number of pages: 1 - The ReNAissanCe of mRNA-based cancer therapy(2015)
Authors: Dries Renmans, Katrijn Broos, Heleen Dewitte, Ine Lentacker, Carlo Heirman, Karine Breckpot, Kris Thielemans
Pages: 235 - 251 - Understanding ultrasound induced sonoporation: definitions and underlying mechanisms(2014)
Authors: Ine Lentacker, Ine De Cock, R Deckers, CTW Moonen
Pages: 49 - 64 - Nanoparticle design to induce tumor immunity and challenge the suppressive tumor microenvironment(2014)
Authors: Heleen Dewitte, Rein Verbeke, Karine Breckpot, Ine Lentacker
Pages: 743 - 758 - Choose your models wisely: how different murine bone marrow-derived dendritic cell protocols influence the success of nanoparticulate vaccines in vitro(2014)
Authors: Heleen Dewitte, Rein Verbeke, Karine Breckpot, Claude Libert, Ine Lentacker
Pages: 138 - 146 - The potential of antigen and TriMix sonoporation using mRNA-loaded microbubbles for ultrasound-triggered cancer immunotherapy(2014)
Authors: Heleen Dewitte, Carlo Heirman, Kris Thielemans, Karine Breckpot, Ine Lentacker
Pages: 28 - 36 - Comparison of gold nanoparticle mediated photoporation: vapor nanobubbles outperform direct heating for delivering macromolecules in live cells(2014)
Authors: Ranhua Xiong, Koen Raemdonck, Karen Peynshaert, Ine Lentacker, Ine De Cock, Andre Skirtach, Kevin Braeckmans
Pages: 6288 - 6296 - Enhancing nucleic acid delivery with ultrasound and microbubbles(2013)Series: Methods in Molecular Biology
Authors: Steven Cool, Bart Geers, Ine Lentacker, Niek Sanders, Manfred Ogris, David Oupicky
Pages: 195 - 204 - Focal delivery of AAV2/1-transgenes into the rat brain by localized ultrasound-induced BBB opening(2013)
Authors: Angelika Alonso, Eileen Reinz, Barbara Leuchs, Juergen Kleinschmidt, Marc Fatar, Bart Geers, Ine Lentacker, Michael G. Hennerici, Stefaan De Smedt, Stephen Meairs
Patents
1 - 2 of 2