Publicaties
Preimplantation genetic testing with HLA matching Vrije Universiteit Brussel
Preimplantation genetic testing-human leukocyte antigen '(PGT-HLA) only' refers to the HLA typing of single or few cells biopsied from in vitro fertilized preimplantation embryos. The aim of the procedure is to establish a pregnancy, in which the fetus is HLA compatible with an affected sibling in need of a hematopoietic stem cell transplantation (HSCT). During PGT-M-HLA, the identification of a HLA-compatible embryo is combined with the ...
Parameters of poor prognosis in preimplantation genetic testing for monogenic disorders Vrije Universiteit Brussel
STUDY QUESTION: What is the likelihood of success of a single cycle of preimplantation genetic testing for monogenic disorders (PGT-M), measured as the cumulative live birth rate (CLBR) and based on various patient demographics?
SUMMARY ANSWER: For all women aged ≤40 years, the CLBR was at least 10% when the number of oocytes was ≥7 (range 10-30%) or was at least 5% when the number of oocytes was ≥3 (range 5-17%).
WHAT IS ...
A systematic review of the views of healthcare professionals on the scope of preimplantation genetic testing KU Leuven
Genome-wide equine preimplantation genetic testing enabled by simultaneous haplotyping and copy number detection KU Leuven
Clinical Guideline for Preimplantation Genetic Testing in Inherited Cardiac Diseases. KU Leuven
Preimplantation genetic testing for aneuploidy by microarray analysis of polar bodies in advanced maternal age Vrije Universiteit Brussel
STUDY QUESTION: Does preimplantation genetic testing for aneuploidy (PGT-A) by comprehensive chromosome screening (CCS) of the first and second polar body to select embryos for transfer increase the likelihood of a live birth within 1 year in advanced maternal age women aged 36-40 years planning an ICSI cycle, compared to ICSI without chromosome analysis?
SUMMARY ANSWER: PGT-A by CCS in the first and second polar body to select ...