Researcher
Peter Marynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-kappaB activation in lymphoma development.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Identification, characterization and analysis of the molecular consequences of mutant protein tyrosine kinase and related genes in leukaemia and lymphoma.From1 Oct 2009 → 30 Sep 2010Funding: Foundations, funds and other with scientific goal
- Cosmopolitan Chicken research project.From1 Jan 2009 → 31 Dec 2010Funding: IWT / VLAIO - excluding impulse programmes
- The marginal zone B cel in concordant xenograft rejection: critical help signals in the T cel-independent type II xenoantibody response and possible targets for xeno-immunosuppression.From1 Oct 2008 → 30 Sep 2013Funding: FWO fellowships
- Elucidating causative genes and pathogenetic mechanisms in cancer: a systems biology approach.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-κB activation in lymphoma development.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
- Causal genomic duplications in patients with mental retardation: role of overexpression of genes on cognition.From1 Jan 2008 → 12 Jun 2012Funding: IWT personal funding - strategic basic research grants
Publications
21 - 30 of 52
- Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs(2010)
Authors: Xavier Sagaert, Thomas Tousseyn, Peter Van Loo, Mathijs Baens, Peter Marynen, Gert De Hertogh, Karel Geboes, Chris Peeters
Pages: 458 - 469 - Novel PORCN mutations in focal dermal hypoplasia(2009)
Authors: Guy Froyen, Hilde Van Esch, Koenraad Devriendt, Jean-Pierre Frijns, Peter Marynen
Pages: 535 - 543 - Dosage-dependent severity of the phenotype in patients with mental retardation due to a recurrent copy-number gain at Xq28 mediated by an unusual recombination(2009)
Authors: Joke Vandewalle, Hilde Van Esch, Jean-Pierre Frijns, Peter Marynen, Guy Froyen
Pages: 809 - 22 - JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma(2009)
Authors: Katrien Van Roosbroeck, Luk Cox, Olga Gielen, Thomas Tousseyn, Barbara Cauwelier, Pascale De Paepe, Peter Vandenberghe, Peter Marynen, Jan Cools, Iwona Krajewska
Pages: 65 - 65 - Computational methods for the detection of cis-regulatory modules(2009)
Authors: Peter Van Loo, Peter Marynen
Pages: 509 - 524 - A20 Negatively Regulates T Cell Receptor Signaling to NF-kappa B by Cleaving Malt1 Ubiquitin Chains(2009)
Authors: Mathijs Baens, Peter Marynen
Pages: 7718 - 7728 - Identification and characterization of oncogenic tyrosine kinases and tyrosine kinase inhibitors(2009)
Authors: Els Lierman, Jan Cools, Peter Marynen
- FIP1L1-PDGFR alpha D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFR alpha T674I eosinophilic leukemia with single agent sorafenib(2009)
Authors: Lucienne Michaux, Peter Marynen, Jan Cools, Peter Vandenberghe
Pages: 845 - 851 - Atonal homolog 1 is a tumor suppressor gene.(2009)
Authors: Wouter Bossuyt, A Kazanjian, Natalie De Geest, S Van Kelst, Gert De Hertogh, Karel Geboes, GP Boivin, J Luciani, F Fuks, Marinee Chuah, et al.
Pages: 311 - 326 - Atonal homolog 1 is a tumor suppressor gene(2009)
Authors: Wouter Bossuyt, Natalie De Geest, Gert De Hertogh, Karel Geboes, Marinee Chuah, Thierry Vandendriessche, Peter Marynen, Jan Cools, Bassem Hassan
Pages: 311 - 326