Researcher
Peter Marynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-kappaB activation in lymphoma development.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Identification, characterization and analysis of the molecular consequences of mutant protein tyrosine kinase and related genes in leukaemia and lymphoma.From1 Oct 2009 → 30 Sep 2010Funding: Foundations, funds and other with scientific goal
- Cosmopolitan Chicken research project.From1 Jan 2009 → 31 Dec 2010Funding: IWT / VLAIO - excluding impulse programmes
- The marginal zone B cel in concordant xenograft rejection: critical help signals in the T cel-independent type II xenoantibody response and possible targets for xeno-immunosuppression.From1 Oct 2008 → 30 Sep 2013Funding: FWO fellowships
- Elucidating causative genes and pathogenetic mechanisms in cancer: a systems biology approach.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-κB activation in lymphoma development.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
- Causal genomic duplications in patients with mental retardation: role of overexpression of genes on cognition.From1 Jan 2008 → 12 Jun 2012Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 52
- Malt1 self-cleavage is critical for regulatory Tcell homeostasis and anti-tumor immunity in mice(2018)
Authors: Rocco Stirparo, Youlia Lampi, Delphine Verbeke, Jan Cools, Peter Marynen, Charles De Bock, Simon Bornschein
Pages: 1728 - 1738 - Small chromosomal regions position themselves autonomously according to their chromatin class(2017)
Authors: Koen Theunis, Parveen Kumar, Peter Marynen, Thierry Voet
Pages: 922 - 933 - Identification of Intellectual Disability Genes in Female Patients with A Skewed X Inactivation Pattern(2016)
Authors: Nathalie Fieremans, Hilde Van Esch, Koenraad Devriendt, Joris Vermeesch, Peter Marynen, Guy Froyen
Pages: 804 - 811 - Nxf7 deficiency impairs social exploration and spatio-cognitive abilities as well as hippocampal synaptic plasticity in mice(2015)
Authors: Tariq Ahmed, Ben Vermaercke, Peter Marynen, Detlef Balschun, Guy Froyen, Rudi D'Hooge
Pages: 179 - De novo MECP2 duplications in two females with intellectual disability and unfavorable complete skewed X-inactivation(2014)
Authors: Peter Marynen
Pages: 1359 - 1367 - Evidence for increased SOX3 dosage as a risk factor for X-linked hypopituitarism and neural tube defects(2014)
Authors: Marijke Bauters, Hilde Van Esch, Marcella Baldewijns, Jean-Pierre Frijns, Peter Marynen, Guy Froyen
Pages: 1947 - 52 - MALT1 Auto-Proteolysis Is Essential for NF-κB-Dependent Gene Transcription in Activated Lymphocytes(2014)
Authors: Mathijs Baens, Stephen Weeks, Peter Marynen
- Ubiquitin Ligase HUWE1 Regulates Axon Branching through the Wnt/beta-Catenin Pathway in a Drosophila Model for Intellectual Disability(2013)
Authors: Joke Vandewalle, Hilde Brems, Marijke Bauters, Elsa Lauwers, Peter Marynen, Patrik Verstreken, Bassem Hassan, Guy Froyen
- The mitochondrial solute carrier SLC25A5 at Xq24 is a novel candidate gene for non-syndromic intellectual disability(2013)
Authors: Marijke Bauters, Hilde Van Esch, Nathalie Fieremans, Koenraad Devriendt, Jean-Pierre Frijns, Peter Marynen, Guy Froyen
Pages: 1177 - 85 - Generation and Characterization of an Nxf7 Knockout Mouse to Study NXF5 Deficiency in a Patient with Intellectual Disability(2013)
Authors: Lieselot Vanmarsenille, Anton Roebroek, Rudi D'Hooge, Peter Marynen, Guy Froyen