Researcher
Peter Marynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-kappaB activation in lymphoma development.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Identification, characterization and analysis of the molecular consequences of mutant protein tyrosine kinase and related genes in leukaemia and lymphoma.From1 Oct 2009 → 30 Sep 2010Funding: Foundations, funds and other with scientific goal
- Cosmopolitan Chicken research project.From1 Jan 2009 → 31 Dec 2010Funding: IWT / VLAIO - excluding impulse programmes
- The marginal zone B cel in concordant xenograft rejection: critical help signals in the T cel-independent type II xenoantibody response and possible targets for xeno-immunosuppression.From1 Oct 2008 → 30 Sep 2013Funding: FWO fellowships
- Elucidating causative genes and pathogenetic mechanisms in cancer: a systems biology approach.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-κB activation in lymphoma development.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
- Causal genomic duplications in patients with mental retardation: role of overexpression of genes on cognition.From1 Jan 2008 → 12 Jun 2012Funding: IWT personal funding - strategic basic research grants
Publications
41 - 50 of 52
- Systems biology: identification ofregulatory regions and disease causing genes and mechanisms(2008)
Authors: Peter Van Loo, Peter Marynen, Bart De Moor, Christiane Peeters
Number of pages: 168 - In vitro validation of gamma-secretase inhibitors alone or in combination with other anti-cancer drugs for the treatment of T-cell acute lymphoblastic leukemia(2008)
Authors: Kim De Keersmaecker, Peter Vandenberghe, Peter Marynen, Jan Cools
Pages: 533 - 542 - ModuleMiner: improved computational detection of cis-regulatory modules. Different modes of gene regulation in embryonic development and adult tissues?(2008)
Authors: Peter Van Loo, Stein Aerts, Bernard Thienpont, Bart De Moor, Yves Moreau, Peter Marynen
- Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation(2008)
Authors: Guy Froyen, Mark Corbett, Joke Vandewalle, Irma Jarvela, Owen Lawrence, Cliff Meldrum, Marijke Bauters, Karen Govaerts, Lucianne Vandeleur, Hilde Van Esch, et al.
Pages: 432 - 443 - Submicroscopic duplications of the hydroxysteroid dehydrogenase HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with mental retardation(2008)
Authors: Guy Froyen, Joke Vandewalle, Marijke Bauters, Hilde Van Esch, Jean-Pierre Frijns, Peter Marynen
Pages: 432 - 443 - Detection and validation of copy number variation in X-linked mental retardation(2008)
Authors: Marijke Bauters, An Weuts, Joke Vandewalle, Joke Nevelsteen, Peter Marynen, Hilde Van Esch, Guy Froyen
Pages: 44 - 53 - Activity of imatinib in systemic mastocytosis with chronic basophilic leukemia and a PRKG2-PDGFRB fusion(2008)
Authors: Jan Cools, Peter Marynen
Pages: 49 - 56 - Genomics of MECP2 duplications(2008)
Authors: Marijke Bauters, Hilde Van Esch, MR Friez, O Boespflug-Tanguy, M Zenker, AM Vianna-Morgante, C Rosenberg, J Ignatius, M Raynaud, K Hollanders, et al.
Pages: 241 - 242 - DNA methylation profiling in patients with mental retardation by chip-on-chip(2008)
Authors: Joke Nevelsteen, Marijke Bauters, Hilde Van Esch, Peter Marynen, Guy Froyen
Pages: 268 - 268 - Detection of genomic copy number changes in patients with idiopathic mental retardation by high-resolution X-array-CGH: Important role for increased gene dosage of XLMR genes(2008)
Authors: Guy Froyen, Marijke Bauters, Suzanna G Frints, Joris Vermeesch, Koenraad Devriendt, Jean-Pierre Fryns, Peter Marynen
Pages: 256 - 257