Researcher
Peter Marynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-kappaB activation in lymphoma development.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Identification, characterization and analysis of the molecular consequences of mutant protein tyrosine kinase and related genes in leukaemia and lymphoma.From1 Oct 2009 → 30 Sep 2010Funding: Foundations, funds and other with scientific goal
- Cosmopolitan Chicken research project.From1 Jan 2009 → 31 Dec 2010Funding: IWT / VLAIO - excluding impulse programmes
- The marginal zone B cel in concordant xenograft rejection: critical help signals in the T cel-independent type II xenoantibody response and possible targets for xeno-immunosuppression.From1 Oct 2008 → 30 Sep 2013Funding: FWO fellowships
- Elucidating causative genes and pathogenetic mechanisms in cancer: a systems biology approach.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-κB activation in lymphoma development.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
- Causal genomic duplications in patients with mental retardation: role of overexpression of genes on cognition.From1 Jan 2008 → 12 Jun 2012Funding: IWT personal funding - strategic basic research grants
Publications
11 - 20 of 52
- Telomere length homeostasis and telomere position effect on a linear human artificial chromosome are dictated by the genetic background(2012)
Authors: Thierry Voet, Peter Marynen, Guy Froyen
Pages: 11477 - 11489 - Copy-Number Gains of HUWE1 Due to Replication- and Recombination-Based Rearrangements(2012)
Authors: Guy Froyen, Peter Marynen
Pages: 252 - 64 - Development and characterization of a linear human chromosomal vector to study increased gene dosage in mice(2012)
Authors: Guy Froyen, Thierry Voet, Peter Marynen
- JAK2 rearrangements, including the novel SEC31A-JAK2 fusion, are recurrent in classical Hodgkin lymphoma(2011)
Authors: Katrien Van Roosbroeck, Thomas Tousseyn, Barbara Cauwelier, Gregor Verhoef, Peter Marynen, Peter Vandenberghe, Jan Cools
Pages: 4056 - 4064 - Identification and characterization of new lymphoma-associated geneticaberrations involving protein tyrosine kinase loci(2010)
Authors: Peter Marynen, Christiane Peeters
Number of pages: 117 - Allele-specific copy number analysis of tumors(2010)
Authors: Peter Van Loo, Peter Marynen
Pages: 16910 - 16915 - Coactivated Platelet-Derived Growth Factor Receptor alpha and Epidermal Growth Factor Receptor Are Potential Therapeutic Targets in Intimal Sarcoma(2010)
Authors: Barbara Dewaele, Beppe Floris, Agnieszka Wozniak, Patrick Schöffski, Peter Marynen, Peter Vandenberghe, Raf Sciot, Maria Debiec-Rychter
Pages: 7304 - 7314 - Co-activated PDGFRA and EGFR are potential therapeutic targets in intimal sarcoma(2010)
Authors: Barbara Dewaele, Beppe Floris, Julio Finalet-Ferreiro, Christopher Fletcher, Jean Michel Coindre, Louis Guillou, Pancras C Hogendoorn, Agnieszka Wozniak, Vanessa Vanspauwen, Patrick Schöffski, et al.
Pages: 7304 - 7314 - T cell/histiocyte rich large B-cell lymphoma shows transcriptional features suggestive of a tolerogenic host immune response(2010)
Authors: Peter Van Loo, Thomas Tousseyn, Daan Dierickx, Isabelle Vanden Bempt, Gregor Verhoef, Peter Marynen, Patrick Matthys, Chris Peeters
Pages: 440 - 448 - Comparative expressed sequence hybridization studies of t(11;18)(q21;q21)-positive and -negative gastric MALT lymphomas reveal both unique and overlapping gene programs(2010)
Authors: Xavier Sagaert, Thomas Tousseyn, Peter Van Loo, Mathijs Baens, Peter Marynen, Gert De Hertogh, Karel Geboes, Chris Peeters
Pages: 458 - 469