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Researcher
Peter Marynen
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 9 of 9
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-kappaB activation in lymphoma development.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project
- Deregulated signaling pathways in cancer: from genetic insights towards targeted therapy.From1 Oct 2010 → 30 Nov 2016Funding: BOF - Concerted Research Project from 1994
- Identification, characterization and analysis of the molecular consequences of mutant protein tyrosine kinase and related genes in leukaemia and lymphoma.From1 Oct 2009 → 30 Sep 2010Funding: Foundations, funds and other with scientific goal
- Cosmopolitan Chicken research project.From1 Jan 2009 → 31 Dec 2010Funding: IWT / VLAIO - excluding impulse programmes
- The marginal zone B cel in concordant xenograft rejection: critical help signals in the T cel-independent type II xenoantibody response and possible targets for xeno-immunosuppression.From1 Oct 2008 → 30 Sep 2013Funding: FWO fellowships
- Elucidating causative genes and pathogenetic mechanisms in cancer: a systems biology approach.From1 Oct 2008 → 30 Sep 2014Funding: FWO fellowships
- Molecular and functional characterization of MALT1- and AP12-MALT1-mediated NF-κB activation in lymphoma development.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
- Causal genomic duplications in patients with mental retardation: role of overexpression of genes on cognition.From1 Jan 2008 → 12 Jun 2012Funding: IWT personal funding - strategic basic research grants
Publications
51 - 52 of 52
- T cell antigen receptor stimulation induces MALT1 paracaspase-mediated cleavage of the NF-kappaB inhibitor A20(2008)
Authors: Mathijs Baens, Peter Marynen
Pages: 263 - 271 - Auto-ubiquitination-induced degradation of MALT1-API2 prevents BCL10 destabilization in t(11;18)(q21;q21)-positive MALT lymphoma
Authors: Peter Marynen, Mathijs Baens