Researcher
Marc De Maeyer
- Disciplines:Analytical biochemistry
Affiliations
- Biochemistry, Molecular and Structural Biology (Division)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 13
- Unravelling the hidden potential of two ORFans from Pseudomonas virus LUZ7From27 Aug 2015 → 22 Oct 2019Funding: BOF - Doctoral projects
- Molecular elucidation of three antibacterial proteins from Pseudomonas phage LUZ19 for biotechnological applicationsFrom1 Oct 2014 → 11 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Rational design of small molecule modulators targeting the transcriptional function of the Salmonella Typhimurium response regulator PhoPFrom1 Oct 2013 → 8 Dec 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Network-based approaches for the indification and mode of action determination of anti-bacterial agents .From1 Jan 2013 → 31 Dec 2016Funding: SBO (Strategic basic research)
- Computer-Aided Development of Biofilm Inhibitors for Slow Release from Metal Organic Frameworks.From1 Oct 2012 → 30 Sep 2016Funding: BOF - Concerted Research Project from 1994
- Computational study of protein-ligand interactions: Case study of SERCA and biofilm involved proteinsFrom1 Oct 2011 → 23 Mar 2017Funding: BOF - Doctoral projects
- Exploiting the BH4 domain of Bcl-2 as a novel target for the development of peptidomimetics that promote pro-apoptotic Ca2+ signaling.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Development of a structural database for improved rational kinase drug design.From1 Nov 2010 → 31 Oct 2011Funding: BOF - Other initiatives
- Unravelling the regulatory roles of defective invertases in plantsFrom1 Oct 2010 → 1 Oct 2014Funding: BOF - Doctoral projects
- A multi-disciplinary approach to exploit pro-apoptotic Ca2+ signaling as a novel anti-cancer strategy.From1 Oct 2010 → 30 Sep 2015Funding: BOF - Concerted Research Project from 1994
Publications
31 - 40 of 68
- Structural and Biochemical Investigation of Leucine-Rich Repeat Kinase 2(2012)
Authors: Renée Vancraenenbroeck, Marc De Maeyer, Veerle Baekelandt, Luc Van Meervelt
Number of pages: 179 - pKa modulation of the acid/base catalyst within GH32 and GH68: a role in substrate/inhibitor specificity?(2012)
Authors: Tom Venken, Wim Van den Ende, Marc De Maeyer
- Identification of a Small Molecule That Modulates Platelet Glycoprotein Ib-von Willebrand Factor Interaction(2012)
Authors: Katleen Broos, Mieke Trekels, Rani Jose, Jonas Demeulemeester, Tom Venken, Brecht Egle, Wim De Borggraeve, Hans Deckmyn, Marc De Maeyer
Pages: 9461 - 9472 - Computational investigation of the HIV-1 Rev multimerization using molecular dynamics simulations and binding free energy calculations(2012)
Authors: Tom Venken, Dirk Daelemans, Marc De Maeyer, Arnout Voet
Pages: 1633 - 1646 - Selective regulation of IP(3)-receptor-mediated Ca(2+) signaling and apoptosis by the BH4 domain of Bcl-2 versus Bcl-Xl(2012)
Authors: Giovanni Monaco, Haidar Akl, Raf Ponsaerts, Tim Vervliet, Marc De Maeyer, Ludwig Missiaen, Humbert De Smedt, Jan Parys, Geert Bultynck
Pages: 295 - 309 - Combined Modeling and Biophysical Characterisation of CO2 Interaction with Class II Hydrophobins: New Insight into the Mechanism Underpinning Primary Gushing(2012)
Authors: Sylvie Deckers, Tom Venken, Mohammadreza Khalesi, Kurt Gebruers, Zahra Shokribousjein, Chris Michiels, Hedwig Neven, Jan Delcour, Johan Martens, Guy Derdelinckx, et al.
Pages: 249 - 256 - De novo design of small molecule inhibitors targeting the LEDGF/p75-HIV integrase interaction(2012)
Authors: Claudia Cavalluzzo, Arnout Voet, Frauke Christ, Zeger Debyser, Marc De Maeyer, Erik Van der Eycken
Pages: 974 - 984 - Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2(2012)
Authors: Renée Vancraenenbroeck, Evy Lobbestael, Stephen Weeks, Sergei Strelkov, Veerle Baekelandt, Jean-Marc Taymans, Marc De Maeyer
Pages: 450 - 460 - Fueling HIV-1 integrase drug design with structural insights(2012)
Authors: Jonas Demeulemeester, Frauke Christ, Marc De Maeyer, Zeger Debyser
Pages: e175 - e226 - An optimized MM/PBSA virtual screening approach applied to an HIV-1 gp41 fusion peptide inhibitor(2011)
Authors: Tom Venken, Marc De Maeyer, Arnout Voet
Pages: 3221 - 35
Patents
1 - 6 of 6
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)