< Back to previous page
Researcher
Evy Lobbestael
- Disciplines:Oncology
Affiliations
- Department of Oncology (Department)
Member
From1 Apr 2022 → Today - Research Group for Neurobiology and Gene Therapy (Division)
Member
From1 Oct 2007 → 30 Nov 2020
Projects
1 - 3 of 3
- Characterisation of LRRK2 kinase function in a-synuclein-induced neurotoxicity and neuroinflammation.From7 Sep 2017 → 31 Oct 2023Funding: FWO fellowships
- The many faces of ATP13A2 in regulating the pathophysiology of alpha-synucleinFrom1 Jun 2016 → 2 Mar 2022Funding: BOF - Doctoral projects
- Insight in the molecular consequenses of LRRK2 kinase inhibition, a kinase involved in Parkinson's disease.From1 Jan 2015 → 13 Jun 2019Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 46
- LRRK2 phosphorylation status and kinase activity regulate (macro)autophagy in a Rab8a/Rab10-dependent manner(2023)
Authors: Rita La Rovere, Evy Lobbestael, Veerle Baekelandt, Geert Bultynck, Jan Parys
- Role of LRRK2 and Inflammation in alpha-Synuclein models of Parkinson's Disease(2023)
Authors: Diego Cabezudo, Veerle Baekelandt, Evy Lobbestael
- The small GTPase Rit2 modulates LRRK2 kinase activity, is required for lysosomal function and protects against alpha-synuclein neuropathology(2023)
Authors: Evy Lobbestael, Veerle Baekelandt
- Increased Levels of the Parkinson's Disease-Associated Gene ITPKB Correlate with Higher Expression Levels of α-Synuclein, Independent of Mutation Status(2023)
Authors: Evy Lobbestael, Veerle Baekelandt
- The many faces of ATP13A2 in regulating the pathophysiology of alpha-synuclein(2022)
Authors: Jianmin Si, Veerle Baekelandt, Chris Van den Haute, Evy Lobbestael
- Protein phosphatase 2A holoenzymes regulate leucine-rich repeat kinase 2 phosphorylation and accumulation(2021)
Authors: Evy Lobbestael, Chris Van den Haute, Veerle Baekelandt
- Multiple-hit hypothesis in Parkinson’s disease: LRRK2 and inflammation(2021)
Authors: Diego Cabezudo, Veerle Baekelandt, Evy Lobbestael
- LRRK2 Ablation Attenuates Αlpha-Synuclein–Induced Neuroinflammation Without Affecting Neurodegeneration or Neuropathology In Vivo(2021)
Authors: Diego Cabezudo, Géraldine Gelders, Chris Van den Haute, Veerle Baekelandt, Evy Lobbestael
Pages: 949 - 961 - ATP13A2 Regulates Cellular α-Synuclein Multimerization, Membrane Association, and Externalization(2021)
Authors: Jianmin Si, Chris Van den Haute, Evy Lobbestael, Sarah van Veen, Peter Vangheluwe, Veerle Baekelandt
- Inflammatory bowel disease and Parkinson's disease: common pathophysiological links(2021)
Authors: Evy Lobbestael, Séverine Vermeire, João Guedelha Sabino, Isabelle Cleynen
Pages: 408 - 417