Researcher
Tim Vervliet
- Disciplines:Cell death, Cell signalling, Molecular and cell biology not elsewhere classified, Cell physiology, Biochemistry and metabolism not elsewhere classified
Affiliations
- Laboratory of Molecular and Cellular Signaling (Division)
Member
From15 Sep 2010 → Today
Projects
1 - 9 of 9
- 'Mito-tracking’ the phenotyping transition of pancreatic stellate cellsFrom1 Oct 2023 → TodayFunding: BOF - projects
- Unraveling the molecular mechanisms underlying Ca2+-signaling modulation by CISD2, a wolfram syndrome-associated gene, and its interplay with Bcl-2 (CaCISD2)From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Regulation of lysosomal function by ryanodine receptormediated Ca2+ release in health and diseaseFrom1 Oct 2020 → TodayFunding: FWO senior postdoctoral fellowship
- Targeting dysregulated IP3 receptor-mediated calcium signaling as an early event in Alzheimer’s disease through its Bcl-2-interaction networkFrom21 Sep 2020 → TodayFunding: FWO fellowships
- IP3R dysregulation as a proximal event in Alzheimer’s disease: exploring and exploiting Bcl-2 proteinsFrom1 Jan 2020 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Molecular mechanisms underlying Ca2+-signaling dysregulation in Wolfram SyndromeFrom1 Oct 2018 → 30 Sep 2020Funding: BOF - Bilateral scientific cooperation
- Elucidating the physiological and patho-physiological role for the interaction of Bcl-2 proteins and the ryanodine receptor.From1 Oct 2016 → 30 Sep 2019Funding: FWO fellowships
- Bcl-2 and ryanodine receptors: physiology, pathophysiology and therapeutics for the heartFrom1 Oct 2016 → 31 Aug 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Novel insights in the interplay between ryanodine receptors and Bcl-2 proteins.From1 Oct 2015 → 30 Sep 2016Funding: BOF - Other initiatives
Publications
1 - 10 of 45
- Neuroprotective properties of anti-apoptotic BCL-2 proteins in 5xFAD mouse model of Alzheimer's disease(2023)
Authors: Manon Callens, Chris Van den Haute, Tim Vervliet, Geert Bultynck
Pages: 273 - 283 - Cardiomyocyte differentiation from human induced pluripotent stem cells is delayed following knockout of Bcl-2(2023)
Authors: Tim Vervliet, Robin Duelen, Rita La Rovere, H Llewelyn Roderick, Maurilio Sampaolesi
- A FACILE METHOD TO GENERATE CEREBRAL ORGANOIDS FROM HUMAN PLURIPOTENT STEM CELLS(2023)
Authors: San Kit To, Vincent Pasque, Tim Vervliet, Yoke Chin Chai, Catherine Verfaillie
Pages: 1055 - 1076 - The alkalinizing, lysosomotropic agent ML-9 induces a pH-dependent depletion of ER Ca2+ stores in cellulo(2022)
Authors: Martijn Kerkhofs, Peter Vangheluwe, Geert Bultynck, Tim Vervliet
- Long-term culture of patient-derived cardiac organoids recapitulated Duchenne muscular dystrophy cardiomyopathy and disease progression(2022)
Authors: Vittoria Marini, Nefele Giarratana, Enrico Pozzo, Robin Duelen, Rita La Rovere, Tim Vervliet, Geert Bultynck, Maurilio Sampaolesi, Yoke Chin Chai
- SOX9-induced Generation of Functional Astrocytes Supporting Neuronal Maturation in an All-human System(2021)
Authors: Katrien Neyrinck, Tim Vervliet, Jonathan De Smedt, Melissa Nijs, Sarah-Maria Fendt, Geert Bultynck, Catherine Verfaillie
Pages: 1855 - 1873 - Uniting the divergent Wolfram syndrome–linked proteins WFS1 and CISD2 as modulators of Ca2+ signaling(2021)
Authors: Jens Loncke, Tim Vervliet, Jan Parys, Geert Bultynck
Pages: 1 - 10 - Fast and Efficient Generation of Isogenic Induced Pluripotent Stem Cell Lines Using Adenine Base Editing(2021)
Authors: FatemehArefeh Nami, Roya Ramezankhani, Marjan Vandenabeele, Tim Vervliet, Catherine Verfaillie
Pages: 502 - 518 - Prdm16 Supports Arterial Flow Recovery by Maintaining Endothelial Function(2021)
Authors: Sander Craps, Jore Van Wauwe, Bram Boeckx, Tim Vervliet, Wouter Dheedene, Nathan Criem, Elizabeth Jones, An Zwijsen, Diether Lambrechts, Aernout Luttun
Pages: 63 - 77 - The role of Bcl-2 proteins in modulating neuronal Ca2+ signaling in health and in Alzheimer's disease(2021)
Authors: Manon Callens, Wim Annaert, Geert Bultynck, Tim Vervliet