Researcher
Giovanni Monaco
- Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences
Affiliations
- Laboratory of Molecular and Cellular Signaling (Division)
Member
From1 Sep 2008 → 21 Jul 2020
Projects
1 - 2 of 2
- Anti-apoptotic regulation of the ER-Mitochondria-Ca2+ cross-talk by Bcl-2 and Bcl-XL: inhibition of Ca2+ channels at the interorganellar contact sites?From1 Oct 2013 → 22 Jul 2019Funding: FWO fellowships
- Regulation of intracellular Ca2+ signalling by the anti-apoptotic Bcl-2-family members.From1 Sep 2008 → 30 Sep 2013Funding: FWO fellowships
Publications
1 - 10 of 27
- Budgeting at the Ca2+ store: a PIP(2)eline to starve LSCs?(2021)
Authors: Giovanni Monaco
- Bcl-2-protein family as modulators of IP₃ receptors and other organellar Ca²⁺ channels(2020)
Authors: Hristina Ivanova, Tim Vervliet, Giovanni Monaco, Nicolas Rosa, Jan Parys, Geert Bultynck
- Therapeutic implications of novel peptides targeting ER-mitochondria Ca2+-flux systems(2019)
Authors: Martijn Kerkhofs, Geert Bultynck, Tim Vervliet, Giovanni Monaco
Pages: 1092 - 1103 - Pathophysiological consequences of isoform-specific IP3 receptor mutations(2018)
Authors: Martijn Kerkhofs, Bruno Seitaj, Hristina Ivanova, Giovanni Monaco, Geert Bultynck, Jan Parys
Pages: 1707 - 1717 - Superoxide Anion Production and Bioenergetic Profile in Young and Elderly Human Primary Myoblasts(2018)
Authors: Rita La Rovere, Giovanni Monaco, Geert Bultynck
- A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for BH4 domain in both protein stability and function(2018)
Authors: Giovanni Monaco, Rita La Rovere, Lily Karamanou, Hristina Ivanova, Elien Vandermarliere, Humbert De Smedt, Jan Parys, Tassos Economou, Geert Bultynck
Pages: 127 - 145 - Modulation of Ca2+ Signaling by Anti-apoptotic B-Cell Lymphoma 2 Proteins at the Endoplasmic Reticulum-Mitochondrial Interface(2017)
Authors: Tim Vervliet, Eva Clerix, Bruno Seitaj, Hristina Ivanova, Giovanni Monaco, Geert Bultynck
- The trans-membrane domain of Bcl-2a, but not its hydrophobic cleft, is a critical determinant for efficient IP3 receptor inhibition(2016)
Authors: Hristina Ivanova, Abigaël Ritaine, Bruno Seitaj, Giovanni Monaco, Humbert De Smedt, Jan Parys, Geert Bultynck
Pages: 55704 - 55720 - Ryanodine receptors are targeted by anti-apoptotic Bcl-XL involving its BH4 domain and Lys87 from its BH3 domain(2015)
Authors: Tim Vervliet, Elien Vandermarliere, Hristina Ivanova, Giovanni Monaco, Ludwig Missiaen, Humbert De Smedt, Jan Parys, Geert Bultynck
- The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria(2015)
Authors: Giovanni Monaco, Elke Decrock, Nir Arbel, Alex van Vliet, Rita La Rovere, Humbert De Smedt, Jan Parys, Patrizia Agostinis, Luc Leybaert, Varda Shoshan-Barmatz, et al.
Pages: 9150 - 9161