Researcher
Marc De Maeyer
- Disciplines:Analytical biochemistry
Affiliations
- Biochemistry, Molecular and Structural Biology (Division)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 13
- Unravelling the hidden potential of two ORFans from Pseudomonas virus LUZ7From27 Aug 2015 → 22 Oct 2019Funding: BOF - Doctoral projects
- Molecular elucidation of three antibacterial proteins from Pseudomonas phage LUZ19 for biotechnological applicationsFrom1 Oct 2014 → 11 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Rational design of small molecule modulators targeting the transcriptional function of the Salmonella Typhimurium response regulator PhoPFrom1 Oct 2013 → 8 Dec 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Network-based approaches for the indification and mode of action determination of anti-bacterial agents .From1 Jan 2013 → 31 Dec 2016Funding: SBO (Strategic basic research)
- Computer-Aided Development of Biofilm Inhibitors for Slow Release from Metal Organic Frameworks.From1 Oct 2012 → 30 Sep 2016Funding: BOF - Concerted Research Project from 1994
- Computational study of protein-ligand interactions: Case study of SERCA and biofilm involved proteinsFrom1 Oct 2011 → 23 Mar 2017Funding: BOF - Doctoral projects
- Exploiting the BH4 domain of Bcl-2 as a novel target for the development of peptidomimetics that promote pro-apoptotic Ca2+ signaling.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Development of a structural database for improved rational kinase drug design.From1 Nov 2010 → 31 Oct 2011Funding: BOF - Other initiatives
- Unravelling the regulatory roles of defective invertases in plantsFrom1 Oct 2010 → 1 Oct 2014Funding: BOF - Doctoral projects
- A multi-disciplinary approach to exploit pro-apoptotic Ca2+ signaling as a novel anti-cancer strategy.From1 Oct 2010 → 30 Sep 2015Funding: BOF - Concerted Research Project from 1994
Publications
41 - 50 of 68
- Experimental validation and docking studies of flavone derivatives on aldose reductase involved in diabetic retinopathy, neuropathy, and nephropathy(2011)
Authors: Marc De Maeyer
Pages: 930 - 945 - Kinases as targets for Parkinson's disease: from genetics to therapy(2011)
Authors: Renée Vancraenenbroeck, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt, Jean-Marc Taymans
Pages: 724 - 740 - Structure based discovery and optimization of first-in-class inhibitors of the HIV-1 IN-LEDGF/p75 interaction(2011)
Authors: Arnout Voet, Frauke Christ, Arnaud Marchand, Patrick Chaltin, Stefan Nicolet, Sergei Strelkov, Zeger Debyser, Marc De Maeyer
Pages: 120 - 121 - LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding(2011)
Authors: Jean-Marc Taymans, Renée Vancraenenbroeck, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt
- Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant(2011)
Authors: Veronique Daniëls, Renée Vancraenenbroeck, Evy Lobbestael, Marc De Maeyer, Veerle Baekelandt, Jean-Marc Taymans
Pages: 304 - 315 - Targeting integration beyond strand transfer: development of second-generation HIV integrase inhibitors(2011)
Authors: Arnout Voet, Marc De Maeyer, Frauke Christ, Zeger Debyser
Pages: 51 - 71 - Structure based discovery of small molecule suppressors targeting bacterial lysozyme inhibitors(2011)
Authors: Arnout Voet, Lien Callewaert, Lise Vanderkelen, Joris Van Herreweghe, Chris Michiels, Marc De Maeyer
Pages: 527 - 532 - Designing Triple Helical Fragments: The Crystal Structure of the Undecamer d(TGGCCTTAAGG) Mimicking T center dot AT Base Triplets(2010)
Authors: Kristof Van Hecke, Arnout Voet, Marc De Maeyer, Luc Van Meervelt
Pages: 4622 - 4629 - Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication(2010)
Authors: Frauke Christ, Arnout Voet, Belete Ayele Desimmie, Sergei Strelkov, Marc De Maeyer, Patrick Chaltin, Zeger Debyser
Pages: 442 - 448 - Development of small molecule protein-protein interaction inhibitors targeting the HIV-1 integrase - LEDGF/p75 complex.(2010)
Authors: Arnout Voet, Marc De Maeyer, Zeger Debyser
Patents
1 - 6 of 6
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)