Researcher
Marc De Maeyer
- Disciplines:Analytical biochemistry
Affiliations
- Biochemistry, Molecular and Structural Biology (Division)
Member
From1 Oct 2004 → Today
Projects
1 - 10 of 13
- Unravelling the hidden potential of two ORFans from Pseudomonas virus LUZ7From27 Aug 2015 → 22 Oct 2019Funding: BOF - Doctoral projects
- Molecular elucidation of three antibacterial proteins from Pseudomonas phage LUZ19 for biotechnological applicationsFrom1 Oct 2014 → 11 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Rational design of small molecule modulators targeting the transcriptional function of the Salmonella Typhimurium response regulator PhoPFrom1 Oct 2013 → 8 Dec 2017Funding: Own budget, for example: patrimony, inscription fees, gifts
- Network-based approaches for the indification and mode of action determination of anti-bacterial agents .From1 Jan 2013 → 31 Dec 2016Funding: SBO (Strategic basic research)
- Computer-Aided Development of Biofilm Inhibitors for Slow Release from Metal Organic Frameworks.From1 Oct 2012 → 30 Sep 2016Funding: BOF - Concerted Research Project from 1994
- Computational study of protein-ligand interactions: Case study of SERCA and biofilm involved proteinsFrom1 Oct 2011 → 23 Mar 2017Funding: BOF - Doctoral projects
- Exploiting the BH4 domain of Bcl-2 as a novel target for the development of peptidomimetics that promote pro-apoptotic Ca2+ signaling.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
- Development of a structural database for improved rational kinase drug design.From1 Nov 2010 → 31 Oct 2011Funding: BOF - Other initiatives
- Unravelling the regulatory roles of defective invertases in plantsFrom1 Oct 2010 → 1 Oct 2014Funding: BOF - Doctoral projects
- A multi-disciplinary approach to exploit pro-apoptotic Ca2+ signaling as a novel anti-cancer strategy.From1 Oct 2010 → 30 Sep 2015Funding: BOF - Concerted Research Project from 1994
Publications
11 - 20 of 68
- Structural elucidation of a novel mechanism for the bacteriophage-based inhibition of the RNA degradosome(2016)
Authors: Hanne Hendrix, Marc De Maeyer, Abram Aertsen, Rob Lavigne
- A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies(2016)
Authors: Anouck Wijgaerts, Kathelijne Peerlinck, Marc De Maeyer, Chris Van Geet, Kathleen Freson
Pages: 328 - Mechanism of Nonpolar Model Substances to Inhibit Primary Gushing Induced by Hydrophobin HFBI(2015)
Authors: Zahra Shokribousjein, David Santiago Riveros Galan, Patrick Wagner, Jeroen Lammertyn, Asefeh Golreihan, Marc De Maeyer, Guy Derdelinckx
Pages: 4673 - 4682 - The novel ADAMTS13-p.D187H mutation impairs ADAMTS13 activity and secretion and contributes to thrombotic thrombocytopenic purpura in mice(2015)
Authors: Joren De Raeymaecker, Hans Deckmyn, Marc De Maeyer, Simon De Meyer, Karen Vanhoorelbeke
Pages: 283 - 92 - LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014)(2014)
Authors: Jonas Demeulemeester, Patrick Chaltin, Arnaud Marchand, Marc De Maeyer, Zeger Debyser, Frauke Christ
Pages: 609 - 632 - In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2(2014)
Authors: Renée Vancraenenbroeck, Joren De Raeymaecker, Evy Lobbestael, Marc De Maeyer, Arnout Voet, Veerle Baekelandt, Jean-Marc Taymans
Pages: 51 - HIV-1 Integrase Drug Discovery Comes of Age(2014)
Authors: Jonas Demeulemeester, Marc De Maeyer, Zeger Debyser
Pages: 1 - 52 - HIV-1 integrase variants retarget viral integration and are associated with disease progression in a chronic infection cohort(2014)
Authors: Jonas Demeulemeester, Sofie Vets, Rik Schrijvers, Paradise Madlala, Marc De Maeyer, Jan De Rijck, Zeger Debyser, Rik Gijsbers
Pages: 651 - 662 - Autolytic degradation of ocriplasmin: a complex mechanism unraveled by mutational analysis(2014)
Authors: Marc De Maeyer
Pages: 215 - 223 - Pharmacophore modeling: advances, limitations, and current utility in drug discovery(2014)
Authors: Xiaoyu Qing, Xiao Yin Lee, Joren De Raeymaecker, Marc De Maeyer, Arnout Voet
Pages: 81 - 92
Patents
1 - 6 of 6
- Thieno[2,3-b]pyridine derivatives as viral replication inhibitors (Inventor)
- Thieno [2, 3-B] pyridine derivatives as viral replication inhibitors (Inventor)
- ;Antiviral compounds (Inventor)
- THIENO [2, 3-B] PYRIDINE DERIVATIVES AS VIRAL REPLICATION INHIBITORS (Inventor)
- VIRAL REPLICATION INHIBITORS (Inventor)
- NOVEL ANTIVIRAL COMPOUNDS (Inventor)