Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 21
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Stereo-controlled synthesis of artificial genetic systems with modified sugar phosphate backboneFrom10 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthesis of nucleoside analogues as antiviral and antibacterial agentsFrom10 Feb 2020 → 10 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Selection of nucleic acids aptamers with four non-canonical bases for biomedical applicationsFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- New genetic systems with four synthetic nucleobases: towards advance therapy and synthetic biologyFrom1 Oct 2018 → 15 Dec 2021Funding: FWO fellowships
- Synthesis and structure determination of phosphonate oligonucleotidesFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
61 - 70 of 94
- Synthesis and biological evaluation of (68)Ga-bis-DOTA-PA as a potential agent for positron emission tomography imaging of necrosis(2013)
Authors: Natalia Dyubankova, Eveline Lescrinier, Yicheng Ni, Guy Bormans, Alfons Verbruggen
Pages: 816 - 822 - Discovery of an Acyclic Nucleoside Phosphonate that Inhibits Mycobacterium tuberculosis ThyX Based on the Binding Mode of a 5-Alkynyl Substrate Analogue(2013)
Authors: Nastia Parchina, Mathy Froeyen, Jef Rozenski, Steven De Jonghe, Yves Briers, Rob Lavigne, Piet Herdewyn, Eveline Lescrinier
Pages: 1373 - 1383 - Synthesis and biological evaluation of 68Ga labeled bis-DOTA-3,3'-(benzylidene)-bis-(1H-indole-2-carbohydrazide) as a PET tracer for in vivo visualization of necrosis(2013)
Authors: Marlein Miranda Cona, Natalia Dyubankova, Eveline Lescrinier, Guy Bormans, Yicheng Ni, Alfons Verbruggen
Pages: 3216 - 3220 - The biolabile 2'-O-pivaloyloxymethyl modification in an RNA helix: an NMR solution structure(2013)
Authors: Eveline Lescrinier, Piet Herdewyn
Pages: 2638 - 2647 - Sedoheptulose accumulation under CO2 enrichment in leaves of Kalanchoë pinnata: a novel mechanism to enhance C and P homeostasis?(2013)
Authors: Johan Ceusters, Christof Godts, Natalia Dyubankova, Eveline Lescrinier, Maurice De Proft, Wim Van den Ende
Pages: 1497 - 1507 - A synthetic substrate of DNA polymerase deviating from the bases, sugar, and leaving group of canonical deoxynucleoside triphosphates(2013)
Authors: Xiaoping Song, Mathy Froeyen, Eveline Lescrinier, Jef Rozenski, Piet Herdewyn
Pages: 416 - 423 - Manninotriose is a major carbohydrate in red deadnettle (Lamium purpureum, Lamiaceae)(2013)
Authors: Eveline Lescrinier, Wim Van den Ende
Pages: 385 - 393 - A PKS/NRPS/FAS hybrid gene cluster from Serratia plymuthica RVH1 encoding the biosynthesis of three broad spectrum, Zeamine-related antibiotics(2013)
Authors: Joleen Masschelein, Ling-Jie Gao, Birgit Uytterhoeven, Chris Lamberigts, Eveline Lescrinier, Jef Rozenski, Piet Herdewyn, Abram Aertsen, Chris Michiels, Rob Lavigne
- Understanding DNA GyraseB ATPase inhibition in the light of structure and ligand-based modelling techniques.(2012)
Authors: Liane Saiz Urra, Mathy Froeyen, Eveline Lescrinier
- Dipeptides as leaving group in the enzyme-catalyzed DNA synthesis(2012)
Authors: Xiaoping Song, Camille Bouillon, Eveline Lescrinier, Piet Herdewyn
Pages: 2685 - 2700