Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
11 - 20 of 21
- Xylo- and lyxo-type phosphonate nucleic acids: Synthesis and structural analysisFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- Structure and folding of XNA aptamers studied by computational and experimental methodsFrom1 Oct 2016 → 4 Oct 2021Funding: BOF - Doctoral projects, FWO Strategic Basic Research Grant
- Development of a xenozyme and an XNA ligase.From1 Oct 2014 → 30 Sep 2018Funding: BOF - Concerted Research Project from 1994
- Rational Design of XNA Processing EnzymesFrom22 Sep 2014 → 6 Oct 2020Funding: BOF - Doctoral projects
- Flavine dependent thymidylate synthase: a target for new antibiotics.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Synthesis of modified nucleotides for application in medicine and biotechnology.From1 Jan 2012 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Application of enzyme substrate analogues: from inhibitors with anti-mycobacterial properties to synthetic genetic polymersFrom1 Oct 2011 → 13 Sep 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Drug development based on Thymidylate Synthase (TS).From1 Jan 2010 → 31 Dec 2013Funding: FWO research project (including WEAVE projects)
- Nucleotides, nucleic acids and their analogues as tools or targets for inhibitor design.From1 Oct 2009 → 30 Sep 2014Funding: BOF - Concerted Research Project from 1994
- Study of the development of peptidomimetics for the inhibition of the interaction of HIV-integrase and the cellular co-factor LEDGF/p75.From1 Jan 2009 → 31 Dec 2014Funding: FWO research project (including WEAVE projects)
Publications
1 - 10 of 93
- Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif(2023)
Authors: Jérôme Rihon, Charles-Alexandre Mattelaer, Piet Herdewyn, Eveline Lescrinier
Pages: 7736 - 7748 - Polyketide Synthase-Mediated O-Methyloxime Formation in the Biosynthesis of the Oximidine Anticancer Agents(2023)
Authors: Eveline Vriens, Dries De Ruysscher, Sofie Dekimpe, Gert Steurs, Ahmed Shemy, Dirk Daelemans, Wim De Borggraeve, Eveline Lescrinier, Joleen Masschelein
- Synthesis, antiviral activity, and computational study of β-D-xylofuranosyl nucleoside phosphonates(2023)
Authors: Yuqing Xu, Elisabetta Groaz, Jérôme Rihon, Piet Herdewyn, Eveline Lescrinier
- The beta2-adrenergic receptor in the apical membrane of intestinal enterocytes senses sugars to stimulate glucose uptake from the gut(2023)
Authors: Eveline Lescrinier, Patrick Van Dijck, Walter Luyten, Johan Thevelein
- Common variable immunodeficiency in two kindreds with heterogeneous phenotypes caused by novel heterozygous NFKB1 mutations(2022)
Authors: Frederik Staels, Emanuela Pasciuto, Eveline Lescrinier, Xavier Bossuyt, Margaux Gerbaux, Julika Neumann, Ingeborg Stalmans, Isabelle Meyts, Adrian Liston, Stephanie Humblet-Baron, et al.
- Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication(2022)
Authors: Laura Vangeel, Erion Lyoo, Eveline Lescrinier, Pieter Leyssen, Dirk Jochmans, Johan Neyts, Steven De Jonghe
- Curing Cats with Feline Infectious Peritonitis with an Oral Multi-Component Drug Containing GS-441524(2021)
Authors: Eveline Lescrinier
- Determination of tacrolimus, three mono-demethylated metabolites and a M1 tautomer in human whole blood by liquid chromatography - tandem mass spectrometry(2021)
Authors: Pieter Annaert, Eveline Lescrinier, Dirk Kuypers
- Structure and folding of XNA aptamers studied by computational and experimental methods(2021)
Authors: Eveline Lescrinier, Mathy Froeyen
- Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site(2021)
Authors: Anne-Sophie Depuydt, Jérôme Rihon, Eveline Lescrinier, Steve Peigneur, Jan Tytgat
Pages: 1 - 11