Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 21
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Stereo-controlled synthesis of artificial genetic systems with modified sugar phosphate backboneFrom10 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthesis of nucleoside analogues as antiviral and antibacterial agentsFrom10 Feb 2020 → 10 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Selection of nucleic acids aptamers with four non-canonical bases for biomedical applicationsFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- New genetic systems with four synthetic nucleobases: towards advance therapy and synthetic biologyFrom1 Oct 2018 → 15 Dec 2021Funding: FWO fellowships
- Synthesis and structure determination of phosphonate oligonucleotidesFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
41 - 50 of 93
- Base pairing involving artificial bases in vitro and in vivo (vol 7, pg 995, 2016)(2016)
Authors: Omprakash Bande, Darren Braddick, Stefano Agnello, Miyeon Jang, Valerie Pezo, Guy Schepers, Jef Rozenski, Eveline Lescrinier, Philippe Marliere, Piet Herdewyn
Pages: 1611 - 1611 - Base pairing involving artificial bases in vitro and in vivo(2016)
Authors: Jef Rozenski, Eveline Lescrinier, Piet Herdewyn
Pages: 995 - 1010 - NMR-based conformational analysis of 2',6-disubstituted uridines and antiviral evaluation of new phosphoramidate prodrugs(2015)
Authors: Fabio Da Paixao Soares, Elisabetta Groaz, Eveline Lescrinier, Johan Neyts, Pieter Leyssen, Piet Herdewyn
Pages: 5809 - 5815 - NMR study on the interaction of the conserved CREX 'stem-loop' in the hepatitis E virus genome with a naphthyridine-based ligand(2015)
Authors: Natalia Dyubankova, Mathy Froeyen, Mikhail Abramov, Henri-Philippe Mattelaer, Piet Herdewyn, Eveline Lescrinier
Pages: 9665 - 9672 - Xylonucleic acid: synthesis, structure, and orthogonal pairing properties(2015)
Authors: Munmun Maiti, Mohitosh Maiti, Shrinivas Dumbre, Eveline Lescrinier, Arnout Ceulemans, Piet Herdewyn
Pages: 7189 - 7200 - Thymydilaat synthases X als doelwitten voor nieuwe antibiotica(2015)
Authors: Eveline Lescrinier, Piet Herdewyn
Number of pages: 149 - Isoguanine and 5-Methyl-Isocytosine Bases, In Vitro and In Vivo(2015)
Authors: Rania Abou El Asrar, Shrinivas Dumbre, Vitor Bernardes Pinheiro, Eveline Lescrinier, Piet Herdewyn
Pages: 5009 - 5022 - Contribution of dihydrouridine in folding of the D-arm in tRNA(2015)
Authors: Natalia Dyubankova, Piet Herdewyn, Eveline Lescrinier
Pages: 4960 - 4966 - Contribution of dihydrouridine in folding of the D-arm in tRNA(2015)
Authors: Natalia Dyubankova, E Sochacka, K Kraszewska, B Nawrot, Piet Herdewyn, Eveline Lescrinier
Pages: 4960 - 4966 - A combination of polyunsaturated fatty acid, nonribosomal peptide and polyketide biosynthetic machinery is used to assemble the zeamine antibiotics(2015)
Authors: Joleen Masschelein, Charlien Clauwers, Karen Stalmans, Wesley Vermaelen, Eveline Lescrinier, Abram Aertsen, Chris Michiels, Rob Lavigne
Pages: 923 - 929