Researcher
Eveline Lescrinier
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences, Bioinformatics and computational biology
Affiliations
- Medicinal Chemistry (Rega Institute) (Division)
Responsible
From1 Aug 2016 → Today - Medicinal Chemistry (Rega Institute) (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 21
- From experimental NMR data towards a software tool to predict optimal sequences for therapeutic morpholino oligonucleotidesFrom15 Jul 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Stereo-controlled synthesis of artificial genetic systems with modified sugar phosphate backboneFrom10 Nov 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Artificial genetic systems with stereocontrolled sugar-phosphate backbone: towards advanced therapy and synthetic biology.From1 Jan 2021 → TodayFunding: FWO research project (including WEAVE projects)
- Molecular modelling tools to design artificial enzymesFrom18 Nov 2020 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- An NMR facility tailored for biomedical researchFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Synthesis of nucleoside analogues as antiviral and antibacterial agentsFrom10 Feb 2020 → 10 Feb 2024Funding: Own budget, for example: patrimony, inscription fees, gifts
- Selection of nucleic acids aptamers with four non-canonical bases for biomedical applicationsFrom1 Jan 2020 → 31 Dec 2020Funding: FWO research grant KAN
- Streamlining the route of phosphonate XNA from chemistry to applicationFrom1 Oct 2019 → 30 Sep 2023Funding: IOF - technology concept exploration, BOF - projects
- New genetic systems with four synthetic nucleobases: towards advance therapy and synthetic biologyFrom1 Oct 2018 → 15 Dec 2021Funding: FWO fellowships
- Synthesis and structure determination of phosphonate oligonucleotidesFrom17 Sep 2018 → 17 Sep 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
71 - 80 of 93
- Exploring alternative leaving groups for enzyme catalyzed DNA synthesis(2012)
Authors: Piet Herdewyn, Eveline Lescrinier
- Design of Bioactive Peptides from Naturally Occurring mu-Conotoxin Structures(2012)
Authors: Marijke Stevens, Steve Peigneur, Natalia Dyubankova, Eveline Lescrinier, Piet Herdewyn, Jan Tytgat
Pages: 31382 - 31392 - Synthesis of Modified Peptidoglycan Precursor Analogues for the Inhibition of Glycosyltransferase(2012)
Authors: Shrinivas Dumbre, Eveline Lescrinier, Piet Herdewyn
Pages: 9343 - 9351 - Structural and biochemical evaluation of natural and modified Nucleic Acids and their interactions with drugs and biomolecules for therapeutic and synthetic biology application(2012)
Authors: Mohitosh Maiti, Piet Herdewyn, Eveline Lescrinier
- Pc16a, the first characterized peptide from Conus pictus venom, shows a novel disulfide connectivity(2012)
Authors: Annelies Van Der Haegen, Steve Peigneur, Natalia Dyubankova, Eveline Lescrinier, Piet Herdewyn, Jan Tytgat
Pages: 106 - 113 - Synthesis and in vitro enzymatic and antiviral evaluation of phosphoramidate d4T derivatives as chain terminators(2012)
Authors: Christophe Pannecouque, Eveline Lescrinier, Anne Giraut, Piet Herdewyn
Pages: 146 - 153 - Influence of the nucleobase and anchimeric assistance of the carboxyl Acid groups in the hydrolysis of amino Acid nucleoside phosphoramidates(2012)
Authors: Munmun Maiti, Servaas Michielssens, Natalia Dyubankova, Mohitosh Maiti, Eveline Lescrinier, Arnout Ceulemans, Piet Herdewyn
Pages: 857 - 868 - Solution structure and conformational dynamics of deoxyxylonucleic acids (dXNA): An orthogonal nucleic acid candidate(2012)
Authors: Mohitosh Maiti, Mikhail Abramov, Eveline Lescrinier, Mathy Froeyen, Arnout Ceulemans, Piet Herdewyn
Pages: 869 - 879 - Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials(2011)
Authors: Eveline Lescrinier, Jef Rozenski, Arthur Van Aerschot
Pages: 5462 - 5467 - Iminodipropionic acid as the leaving group for DNA polymerization by HIV-1 reverse transcriptase(2011)
Authors: Xiaoping Song, Camille Bouillon, Eveline Lescrinier, Piet Herdewyn
Pages: 1868 - 1880