Organisation
Research Group Molecular Neurobiology (VIB-KU Leuven)
Division
Major research questions focus on cell type vulnerability and single-cell heterogeneity, protein aggregation and proteopathic stress, synaptic function, as well as microglial activation and neuroimmunology.
Sub-organisation(s)
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- Laboratory of Interneuron Developmental Dynamics (VIB-KU Leuven)
- Laboratory of Sleep and Synaptic Plasticity (VIB-KU Leuven)
- Laboratory of Proteolytic Mechanisms in Neurodegeneration (VIB-KU Leuven)
- Laboratory of Neuronal Communication (VIB-KU Leuven)
- Laboratory of Neuronal Differentiation (VIB-KU Leuven Center for Brain & Disease Research)
- Laboratory of Emotional Circuit Development (VIB-KU Leuven)
- Laboratory of Membrane Trafficking (VIB-KU Leuven)
- Laboratory of Stem Cell and Developmental Neurobiology (VIB-KU Leuven)
- Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven)
- Laboratory of Glia Biology (VIB-KU Leuven)
Current researchers
1 - 7 of 7 results
- Patrik Verstreken (Responsible)
- Natalia Gunko (Member)
- Véronique Hendrickx (Member)
- Esther Klingler (Member)
- Sebastian Munck (Member)
- Nicolas Peredo (Member)
- Angéle Pouwels (Member)
Projects
1 - 10 of 22
- Replace a broken freeze substitution low temperature embedding system for light and electron microscopy (Leica EM AFS2)From1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Flanders BioImaging: Leading Imaging Application Integrated Service and Enablement (FBI-LIAISE)From1 Jan 2023 → TodayFunding: FWO International research infrastructure (IRI)
- Single-objective light sheet instrument for fast and highthroughput imaging of 3D tissueFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- 3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MINDFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- FB-III (“FB triple-I”) : Flanders BioImaging: Integrating Imaging Infrastructure from cell to man.From1 Feb 2021 → TodayFunding: FWO International research infrastructure (IRI)
- Dynamic super-resolution microscopy: a gateway for cell biologists to understand molecular machines at work in living cells during homeostasis & diseaseFrom1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
- Development of new chemical tools to investigate the role of L-type calcium channels in diseases.From6 Oct 2020 → TodayFunding: FWO Strategic Basic Research Grant
- A 200 kV transmission electron microscope for high-resolution determination of 3D-ultrastructure of native proteins, cells and tissueFrom1 May 2020 → TodayFunding: FWO Medium Size Research Infrastructure
- Development of an interdisciplinary platform for spatial multi-omic analysis of single cellsFrom1 Oct 2019 → 30 Sep 2023Funding: BOF - projects
- Structural bases of γ-secretase processivity in Familial Alzheimer's DiseaseFrom1 Feb 2019 → 1 Feb 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
21 - 30 of 168
- Integration of Microfractionation, qNMR and Zebrafish Screening for the In Vivo Bioassay-Guided Isolation and Quantitative Bioactivity Analysis of Natural Products(2013)
Authors: Sebastian Munck, Camila Esguerra, Peter de Witte, Alex Crawford
- Comparative motif discovery combined with comparative transcriptomics yield accurate targetome and enhancer predictions(2013)
Authors: Marina Naval Sanchez, Delphine Potier, Sebastian Munck, Bram Van de Sande, Valerie Christiaens, Stein Aerts
Pages: 74 - 88 - Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling(2014)
Authors: Natalie De Geest, Alessia Soldano, Sebastian Munck, Bassem Hassan
- A workflow for streamlined acquisition and correlation of serial regions of interest in array tomography(2021)
Authors: Christopher Cawthorne, Emiel Michiels, Dorien Vandael, Sebastian Munck
- Axonal Odorant Receptors Mediate Axon Targeting(2019)
Authors: Sebastian Munck, Bart De Strooper
Pages: 4334 - + - β-arrestin 2 regulates Aβ generation and γ-secretase activity in Alzheimer's disease(2013)
Authors: Amantha Thathiah, Yunhong Huang, Sebastian Munck, Bart De Strooper
Pages: 43 - 49 - Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents(2014)
Authors: Tariq Ahmed, Sebastian Munck, Detlef Balschun, Carlos Dotti
Pages: 902 - 17 - From Pictures to Knowledge, Bio-Image Informatics Coming of Age(2016)
Authors: Sebastian Munck
Number of pages: 2 - Inhibition of FK506 binding proteins reduces alpha-synuclein aggregation and Parkinson's disease-like pathology(2010)
Authors: Angélique Deleersnijder, Veronique Daniëls, Sarah Schreurs, Sebastian Munck, Veerle Reumers, Hans Pottel, Yves Engelborghs, Chris Van den Haute, Jean-Marc Taymans, Zeger Debyser, et al.
Pages: 2454 - 2463 - Rectal organoid morphology analysis (ROMA) as a promising diagnostic tool in cystic fibrosis(2021)
Authors: Senne Cuyx, Anabela Santo Ramalho Venâncio, Steffen Fieuws, Kaline Arnauts, Marc Ferrante, Catherine Verfaillie, Sebastian Munck, Mieke Boon, Marijke Proesmans, Lieven Dupont, et al.
Pages: 1146 - 1149