Researcher
Carlos Dotti
- Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing, Laboratory medicine
Affiliations
- Research Group Molecular Neurobiology (VIB-KU Leuven) (Division)
Member
From1 Jan 2019 → 31 Dec 2019 - Laboratory of Neuronal Differentiation (VIB-KU Leuven Center for Brain & Disease Research) (Lab)
Member
From1 Jan 2017 → 31 Dec 2018 - Department of Human Genetics (Department)
Member
From1 Apr 2009 → 31 Dec 2016
Projects
1 - 6 of 6
- Combating age-dependent deficits in synaptic plasticity and cognition by preventing cholesterol loss in the neuronal plasma membrane.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- Microglia as a missing link in the embryological development of neuropsychiatric disorders.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project
- Mechanism of neuronal survival during aging: relationship to performance.From1 Oct 2011 → 31 Oct 2012Funding: BOF - Other initiatives
- Molecular determinants of axon-dendrite specification in relation to neuronal migration and mental retardation disorders.From1 Jan 2010 → 31 Dec 2015Funding: FWO research project
- Characterization of aging genes in Drosophila nervous systemFrom1 Oct 2009 → 1 Oct 2013Funding: Own budget, for example: patrimony, inscription fees, gifts
- Functional Peptidomics Knowledge Platform.From1 Oct 2009 → 30 Sep 2013Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 70
- Radial somatic F-actin organization affects growth cone dynamics during early neuronal development(2019)
Authors: Durga Praveen Meka, Robin Scharrenberg, Bing Zhao, Oliver Kobler, Theresa Koenig, Irina Schaefer, Birgit Schwanke, Sergei Klykov, Melanie Richter, Dennis Eggert, et al.
- Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism(2019)
Authors: Adrian Martin-Segura, Alvaro Casadome-Perales, Pietro Fazzari, Jose Manuel Mas, Laura Artigas, Raquel Valls, Angel R Nebreda, Carlos Dotti
- Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization(2019)
Authors: Sebastian Munck, Detlef Balschun, Carlos Dotti
- Increased Insoluble Amyloid-beta Induces Negligible Cognitive Deficits in Old App(NL /NL) Knock-In Mice(2018)
Authors: Rudi D'Hooge, Carlos Dotti, Bart De Strooper
Pages: 801 - 809 - High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease(2018)
Authors: Isabel Salas Hernández, Akila Weerasekera, Tariq Ahmed, Uwe Himmelreich, Rudi D'Hooge, Detlef Balschun, Bart De Strooper, Carlos Dotti
Pages: 82 - 96 - Could blocking the formation of amyloid channels rescue Alzheimer's phenotype?(2018)
Authors: Carlos Dotti
Pages: 7 - 9 - Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity (vo20l 12, e0171968, 2017)(2017)
Authors: Isabel H Salas, Zsuzsanna Callaerts-Végh, Amaia M Arranz, Francesc X Guix, Rudi D'Hooge, Jose A Esteban, Bart De Strooper, Carlos Dotti
- Tetraspanin 6: A novel regulator of hippocampal synaptic transmission and long term plasticity (Vol 12, e0171968, 2017)(2017)
Authors: Isabel H Salas, Zsuzsanna Callaerts-Végh, Amaia M Arranz, Francesc X Guix, Rudi D'Hooge, Jose AA Esteban, Bart De Strooper, Carlos Dotti
- Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival(2017)
Authors: Stefano Benvegnu, Maria Ines Mateo, Ernest Palomer, Jeronimo Jurado-Arjona, Carlos Dotti
Pages: 358 - + - Neuronal p38 alpha mediates synaptic and cognitive dysfunction in an Alzheimer's mouse model by controlling beta-amyloid production(2017)
Authors: Sandra Colie, Sara Sarroca, Rocio Palenzuela, Idoia Garcia, Ander Matheu, Ruben Corpas, Carlos Dotti, Jose A Esteban, Coral Sanfeliu, Angel R Nebreda