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Organisation
Research Group Molecular Neurobiology (VIB-KU Leuven)
Division
Main organisation:Department of Neurosciences
Lifecycle:1 Jan 2017 → Today
Organisation profile:
Major research questions focus on cell type vulnerability and single-cell heterogeneity, protein aggregation and proteopathic stress, synaptic function, as well as microglial activation and neuroimmunology.
Keywords:Neurobiology
Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing, Laboratory medicine
Projects
11 - 20 of 22
- Flanders Bioimaging: towards an integrated, translational and multimodal imaging platform from molecule to man.From1 Feb 2019 → 31 Jan 2021Funding: FWO International research infrastructure (IRI)
- Single-cell omics in high throughput and at spatial resolutionFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Defining the mechanisms of osteo-angiogenic coupling in bone development, homeostasis and fracture repairFrom6 Feb 2018 → 6 Feb 2022Funding: Own budget, for example: patrimony, inscription fees, gifts
- 3D super-resolution correlative light and electron microscopy on a dedicated CLEM microscope and development of an automated data acquisitionFrom1 Sep 2017 → 30 Mar 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- Stress-dependent mental disorders: a molecular and structural basisFrom1 Jan 2017 → 31 Aug 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Repair and upgrade of the high resolution biological SEMFrom1 Oct 2016 → 30 Sep 2018Funding: Fund Recuperation Fiscal Exemption
- Combating age-dependent deficits in synaptic plasticity and cognition by preventing cholesterol loss in the neuronal plasma membrane.From1 Jan 2014 → 31 Dec 2017Funding: FWO research project (including WEAVE projects)
- A CDS (Cellular-Distribution-System) empowering the cell biologist with cell-spatial statistical analysis for describing protein distributions.From1 Oct 2012 → 30 Sep 2015Funding: BOF - Doctoral projects
- Membrane changes in cancer cells: a biophysical and functional study.From1 Oct 2010 → 6 Jul 2017Funding: Nonprofit institution or equivalents, IWT personal funding - strategic basic research grants
- Functional Peptidomics Knowledge Platform.From1 Oct 2009 → 30 Sep 2013Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 168
- An accelerated procedure for approaching and imaging of optically branded region of interest in tissue(2021)
Authors: Natalia Gunko
Pages: 205 - 221 - Aging Increases Hippocampal DUSP2 by a Membrane Cholesterol Loss-Mediated RTK/p38MAPK Activation Mechanism(2019)
Authors: Adrian Martin-Segura, Alvaro Casadome-Perales, Pietro Fazzari, Jose Manuel Mas, Laura Artigas, Raquel Valls, Angel R Nebreda, Carlos Dotti
- Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development(2010)
Authors: Carlos Dotti
Pages: 1343 - 1357 - Glutamatergic Synapse Formation is Promoted by alpha 7-Containing Nicotinic Acetylcholine Receptors(2012)
Authors: Adrian F Lozada, Xulong Wang, Natalia Gunko, Kerri A Massey, Jingjing Duan, Zhaoping Liu, Darwin K Berg
Pages: 7651 - 7661 - Induction of Dendritic Spines by beta 2-Containing Nicotinic Receptors(2012)
Authors: Natalia Gunko
Pages: 8391 - 8400 - Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex(2009)
Authors: Carlos Dotti
Pages: 15344 - 9 - The XLMR gene ACSL4 plays a role in dendritic spine architecture(2009)
Authors: Carlos Dotti
Pages: 657 - 69 - High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A(2014)
Authors: Carlos Dotti
Pages: 864 - 875 - APLP2 regulates neuronal stem cell differentiation during cortical development(2013)
Authors: Bassem Hassan, Carlos Dotti, Bart De Strooper, Annette Gärtner
Pages: 1268 - 77 - Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis(2011)
Authors: Paul P Van Veldhoven, Carlos Dotti
Pages: 1308 - 1315