Specific Congenital Malformations after Exposure to Cyclophosphamide, Epirubicin and 5-Fluorouracil during the First Trimester of Pregnancy Vrije Universiteit Brussel
The treatment of pregnant women with chemotherapeutic drugs leads to congenital malformations in 10-20% of newborn children. We present a case of an ongoing 19-week-long pregnancy which was diagnosed in a 39-year-old woman who was being treated with CEF (cyclophosphamide, epirubicin, 5-fluorouracil) chemotherapy for an infiltrating ductal carcinoma of the breast. After termination of the pregnancy, subsequent examination of the fetus revealed ...