Projects
The effect of incarceration on legal and illegal drug use patterns Ghent University
Drug use in prison is a contemporary problem. International research points at important changes in frequency and manners of use, caused by the effect of incarceration. Tension factors, susch as overcrowding, play a role regarding changing drug use patterns. There are no Belgian studies on this topic. This research will measure the effect of incarceration on the legal and illegal drug use patterns.
Development, evaluation and optimization of ocular drug delivery concepts for the use in dry eye syndrome and retinal disorders. University of Antwerp
Sewage analysis as an alternative methodology to estimate drug use in general population. University of Antwerp
Community-wide assessment of the opioid burden through combined use of wastewater-based analytics and prescription drug monitoring data. University of Antwerp
Monitoring recreational use of emerging (il)licit drugs in communities through the analysis of urban wastewater with a focus on new trends and substances. University of Antwerp
Experimental evolution in Candida biofilms: does drug tolerance facilitate drug resistance development in fungi?Experimental evolution in Candida biofilms: does drug tolerance facilitate drug resistance development in fungi? KU Leuven
Invasive fungal infections pose a profound and growing public health threat with treatment failure and mortality estimates often surpassing 50%. Only three major antifungal drug classes are available to treat lethal fungemia and the incidence of resistance to these drugs has risen significantly in recent years. Moreover, multidrug resistant (MDR) ‘superbugs’ like Candida auris have emerged. Despite these alarming concerns, fungal infections ...
ORDECA – ORganoid Drug screening for Endometrial CAncerIdentifying novel drugs and biomarkers for treating endometrial cancer using a high-throughput patient-derived organoid drug discovery and screening platform KU Leuven
Pharmacometric models to improve therapeutic drug monitoring of monoclonal antibodies in the treatment of inflammatory bowel diseases KU Leuven
Inflammatory bowel diseases (IBD) are chronic, relapsing, inflammatory conditions of the gastrointestinal (GI) tract. Ulcerative colitis (UC) and Crohn’s disease (CD) are the primary subtypes of IBD. Although the etiology remains incompletely understood, it is generally accepted that IBD is the result of an inappropriate host response to environmental factors in genetically susceptible individuals. In Western Europe, prevalence of UC is ...