Researcher
Paul Cos
- Research interest:In vitro and in vivo biofilm assays, Integrated antimicrobial (bacteria, fungi, yeasts and parasites) screening and profiling of pure compounds and extracts, targeting redox homeostasis in mycobacteria
- Keywords:MICROBIOLOGY, BACTERIOLOGY, BIOFILMS, INFLAMMATION, Pharmacy and pharmacology
- Disciplines:Microbiology, Systems biology, Laboratory medicine
- Research techniques:In vitro and in vivo (pre-clinical) models of infectious diseases (bacteria and fungi), evaluation of drugs
- Users of research expertise:Pharmaceutical companies (big pharma, SME, spin-off), news agencies, journalists, government agencies, regulatory (EU) agencies, non-governmental organisations in the field of infectious diseases
Affiliations
- Laboratory for Microbiology, Parasitology and Hygiene (LMPH) (Research group)
Responsible
From1 Oct 2020 → Today - Laboratory for Microbiology, Parasitology and Hygiene (LMPH) (Research group)
Member
From1 Oct 2006 → 30 Sep 2020
Projects
1 - 10 of 53 results
- Implementation of in vivo models to identify potential candidates for treatment of Dry Eye DiseaseFrom1 Oct 2021 → TodayFunding: BOF - projects
- Persistence in Streptococcus pneumoniae infections: elucidation of the importance of persister cells in chronic and recurrent infectionsFrom1 Nov 2020 → TodayFunding: FWO fellowships
- In vivo evaluation of biofilm-related pneumonia.From1 Oct 2020 → 30 Sep 2021Funding: BOF - projects
- Springboard for excellence in advanced development of antibacterials (SPRINGBOARD).From1 Sep 2020 → TodayFunding: H2020 - Spreading excellence and widening participation
- 3D printing of drug loaded medical devices for personalized medicine.From1 May 2020 → TodayFunding: IOF - technology concept exploration
- The exploration of novel rapid technologies and alternatives to conventional microbiological test approaches (μRATE).From1 Apr 2020 → TodayFunding: VLAIO - research project companies
- iMI-project - support - RespiriTB and RaspiriNTMFrom1 Jan 2020 → TodayFunding: IOF - technology concept exploration
- A platform to functionally assess clinically relevant respiratory parameters in small animal models for infectious and non-infectious pulmonary research.From1 Jan 2020 → TodayFunding: BOF - scientific equipment program
- RNA biomarkers discovery for ultra-fast drug synergy and susceptibility testing in the mycobacterium avium complex.From1 Jan 2020 → 31 Oct 2020Funding: BOF - doctoral mandates
- Exploitation of key enzymes of the mycothiol biosynthesis to improve treatment of mycobacterium avium complex infections.From1 Nov 2019 → TodayFunding: FWO Strategic Basic Research Grant
Publications
1 - 10 of 223 results
- Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors(2021)
Authors: Dries De Ruysscher, Luping Pang, Stijn M.G. Lenders, Davie Cappoen, Paul F R C M Cos, Jef Rozenski, Sergei V. Strelkov, Stephen D. Weeks, Arthur Van Aerschot
Number of pages: 17 - Bioassay-guided isolation of antiplasmodial and antimicrobial constituents from the roots of Terminalia albida(2021)
Authors: Mamadou Balde, Emmy Tuenter, An Matheeussen, Mohamed Sahar Traoré, Paul F R C M Cos, Louis Maes, Aïssata Camara, Mamadou Saliou Telly Diallo, Elhadj Saïdou Baldé, Mamadou Aliou Balde, et al.
Number of pages: 7 - Differential induction pattern towards classically activated macrophages in response to an immunomodulatory extract from Pleurotus ostreatus mycelium(2021)
Authors: Gabriel Llauradó Maury, Humberto Morris-Quevedo, Annick Heykers, Ellen Lanckacker, Davie Cappoen, Peter Delputte, Wim Vanden Berghe, Zelen Salgueiro, Paul F R C M Cos
Number of pages: 15 - Novel flavonol-3-O-methylethers from Zanthoxylum pistaciifolium Griseb. (Rutaceae)(2021)
Authors: Yamilé Heredia Díaz, Emmy Tuenter, Jesús Garcia-Díaz, Ania Ochoa Pacheco, Paul F R C M Cos, Luc Pieters, Julio César Escalona Arranz
Pages: 1 - 10 - Gaining a better understanding of the extrusion process in fused filament fabrication 3D printing(2021)
Authors: Bahaa Shaqour, Mohammad Abuabiah, Salameh Abdel-Fattah, Adel Juaidi, Ramez Abdallah, Waleed Abuzaina, Mohammad Qarout, Bart Verleije, Paul F R C M Cos
Pages: 1 - 13 - Restoration of liver function in malnourished mice orally administered with Pleurotus ostreatus fruiting bodies extract(2020)
Authors: Gabriel Llaurado, Yaixa Beltran, Humberto J. Morris, Ebert Marcos, Usnavia Diaz, Jane Marcos, Jesus Garcia, Dunilka Disotuar, Paul F R C M Cos
Pages: 32 - 42 - Trypanocidal potentialities of skimmianine an alkaloid isolated from Zanthoxylum pistaciifolium griseb leaves(2020)
Authors: Yamile Heredia Diaz, Julio Cesar Escalona Arranz, Rosalia Gonzalez Fernandez, Ania Ochoa Pacheco, Jesus Garcia Diaz, Lianet Monzote Fidalgo, Denise da Gama Jaen Batista, Cristiane Franca da Silva, Paul F R C M Cos
Pages: 322 - 327 - Essential oil from Melaleuca leucadendra(2020)
Authors: Lianet Monzote, Alexander M. Scherbakov, Ramón Scull, Prabodh Satyal, Paul F R C M Cos, Andrey E. Shchekotikhin, Lars Gille, William N. Setzer
Number of pages: 13 - Antimicrobial investigation of ethnobotanically selected Guinean plant species(2020)
Authors: Mamadou Aliou Baldé, Emmy Tuenter, Mohamed Sahar Traoré, An Matheeussen, Paul F R C M Cos, Louis Maes, Aïssata Camara, Nyanga Luopou Haba, Kalaya Gomou, Mamadou Saliou Telly Diallo, et al.
Number of pages: 11 - In vitro and in vivo evaluation of in silico predicted pneumococcal UDPG:PP inhibitors(2020)
Authors: Freya Cools, Dhoha Triki, Nele Geerts, Peter Delputte, Denis Fourches, Paul F R C M Cos
Pages: 1 - 12