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Researcher
Patrick Augustijns
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Responsible
From1 Jan 2012 → Today - Drug Delivery and Disposition (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 41
- The impact of advanced age and age-related diseases on drug absorptionFrom10 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PBPK modelling of drug absorption in elderlyFrom8 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanistic in silico modelling of colonic drug absorptionFrom1 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Towards enhanced translational colon-specific in vitro tissue models for assessment of drug disposition, metabolism and safetyFrom23 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Improving preclinical assays to enhance the prediction of the in vivo behavior of oral drug productsFrom8 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Evaluating the impact of advanced age and age-related diseases on gastrointestinal drug behaviour and on the biochemical barrier of the intestinal mucosaFrom17 May 2021 → 2 Sep 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Drug disposition in healthy volunteers and colorectal cancer patientsFrom11 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Drug Absorption in Geriatric Patients and Older People: a training network innovating drug development for the advanced age populationFrom1 Jan 2021 → TodayFunding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Boosting advanced doctoral training in innovative colon targeting drugsFrom1 Jan 2021 → TodayFunding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Multi-dimensional liquid chromatography for the analysis of complex samples.From1 Jan 2021 → TodayFunding: BOF - scientific equipment program
Publications
1 - 10 of 345
- HIV protease inhibitors Nelfinavir and Lopinavir/Ritonavir markedly improve lung pathology in SARS-CoV-2-infected Syrian hamsters despite lack of an antiviral effect.(2022)
Authors: Rana Abdelnabi, Suzanne Kaptein, Sebastiaan ter Horst, Leen Delang, Joana Duarte Da Rocha Pereira, Lotte Coelmont, Kai Henrik Dallmeier, Valentijn Vergote, Laura Vangeel, Pieter Annaert, et al.
Pages: 105311 - The effect of esomeprazole on the upper GI tract release and systemic absorption of mesalazine from colon targeted formulations(2022)
Authors: Arno Van Camp, Tim Vanuytsel, Joachim Brouwers, Patrick Augustijns
Number of pages: 9 - Integration of advanced methods and models to study drug absorption and related processes: An UNGAP perspective.(2022)
Authors: Patrick Augustijns, Thomas de Waal
Pages: 106100 - Practical and operational considerations related to paediatric oral drug formulation: An industry survey.(2022)
Authors: Matthias Van der Veken, Joachim Brouwers, Patrick Augustijns
Pages: 121670 - Application of In Vivo Imaging Techniques and Diagnostic Tools in Oral Drug Delivery Research(2022)
Authors: Patrick Augustijns, Christophe Matthys
Number of pages: 36 - Best practices in current models mimicking drug permeability in the gastrointestinal tract - An UNGAP review.(2022)
Authors: Patrick Augustijns, Joachim Brouwers
Pages: 106098 - The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern(2022)
Authors: Rana Abdelnabi, Dirk Jochmans, Laura Vangeel, Steven De Jonghe, Patrick Augustijns, Birgit Weynand, Johan Neyts
Number of pages: 9 - An Assessment of Occasional Bio-Inequivalence for BCS1 and BCS3 Drugs: What are the Underlying Reasons?(2022)
Authors: Patrick Augustijns
Pages: 124 - 134Number of pages: 11 - The Influence of Fed State Lipolysis Inhibition on the Intraluminal Behaviour and Absorption of Fenofibrate from a Lipid-Based Formulation(2022)
Authors: Marlies Braeckmans, Joachim Brouwers, Jan Tack, Patrick Augustijns
Number of pages: 12 - Fasted intestinal solubility limits and distributions applied to the biopharmaceutics and developability classification systems.(2022)
Authors: Patrick Augustijns, Joachim Brouwers
Pages: 160 - 169