Researcher
Patrick Augustijns
- Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences
Affiliations
- Drug Delivery and Disposition (Division)
Responsible
From1 Jan 2012 → Today - Drug Delivery and Disposition (Division)
Member
From1 Oct 1999 → Today
Projects
1 - 10 of 38 results
- Mechanistic in silico modelling of colonic drug absorptionFrom1 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Improving preclinical assays to enhance the prediction of the in vivo behavior of oral drug productsFrom8 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Evaluating the impact of advanced age and age-related diseases on gastrointestinal drug behaviour and on the biochemical barrier of the intestinal mucosaFrom17 May 2021 → 2 Sep 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Drug disposition in healthy volunteers and colorectal cancer patientsFrom11 Mar 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multi-dimensional liquid chromatography for the analysis of complex samples.From1 Jan 2021 → TodayFunding: BOF - scientific equipment program
- Drug Absorption in Geriatric Patients and Older People: a training network innovating drug development for the advanced age populationFrom1 Jan 2021 → TodayFunding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Boosting advanced doctoral training in innovative colon targeting drugsFrom1 Jan 2021 → TodayFunding: H2020 - Skills and Career Development (Marie Skłodowska-Curie) actions
- Drug solubility in human intestinal fluids: multi-objective analysis and modellingFrom1 Oct 2020 → TodayFunding: BOF - projects
- Pediatric biopharmaceutics: translating gastrointestinal characteristics into improved predictive absorption tools.From1 Jan 2019 → TodayFunding: FWO research project
- Towards a deeper understanding of physiological factors affecting drug and formulation behavior in the human gastrointestinal tractFrom1 Oct 2018 → 2 Nov 2020Funding: FWO fellowships
Publications
1 - 10 of 324 results
- Association between duodenal bile salts and gastric emptying in patients with functional dyspepsia.(2021)
Authors: Lucas Wauters, Matthias Ceulemans, Maarten Lambaerts, Alison Accarie, Joran Toth, Raf Mols, Patrick Augustijns, Jan Tack, Tim Vanuytsel
Pages: 2208 - 2210 - UNGAP best practice for improving solubility data quality of orally administered drugs.(2021)
Authors: M Vertzoni, J Alsenz, Patrick Augustijns, A Bauer-Brandl, Cas Bergström, J Brouwers, A Müllerz, G Perlovich, C Saal, K Sugano, et al.
Pages: 106043 - The combined treatment of Molnupiravir and Favipiravir results in a potentiation of antiviral efficacy in a SARS-CoV-2 hamster infection model(2021)
Authors: Rana Abdelnabi, Caroline S Foo, Suzanne Kaptein, Xin Zhang, Thuc Nguyen Dan Do, Lana Langendries, Laura Vangeel, Judith Breuer, Juanita Pang, Rachel Williams, et al.
Number of pages: 9 - Effect of obesity on gastrointestinal transit, pressure and pH using a wireless motility capsule(2021)
Authors: Nele Steenackers, Lucas Wauters, Bart Van Der Schueren, Patrick Augustijns, Gwen Falony, Mirko Koziolek, Matthias Lannoo, Ann Mertens, Ann Meulemans, Jeroen Raes, et al.
Pages: 1 - 8Number of pages: 8 - Impact of gastrointestinal tract variability on oral drug absorption and pharmacokinetics: An UNGAP review(2021)
Authors: Zahari Vinarov, Mohammad Abdallah, Jose AG Agundez, Karel Allegaert, Abdul W Basit, Marlies Braeckmans, Jens Ceulemans, Maura Corsetti, Brendan T Griffin, Michael Grimm, et al.
Number of pages: 33 - Fasted and fed state human duodenal fluids: Characterization, drug solubility, and comparison to simulated fluids and with human bioavailability(2021)
Authors: D Dahlgren, M Venczel, J-P Ridoux, C Skjold, A Mullertz, R Holm, Patrick Augustijns, PM Hellstrom, H Lennernas
Pages: 240 - 251Number of pages: 12 - Exploring the Impact of Intestinal Fluid Components on the Solubility and Supersaturation of Danazol(2021)
Authors: Cecilie Maria Madsen, Jakob Plum, Bart Hens, Patrick Augustijns, Anette Mullertz, Thomas Rades
Pages: 2479 - 2488Number of pages: 10 - Crystallization Kinetics in Fasted-State Simulated and Aspirated Human Intestinal Fluids(2021)
Authors: Ahmed Elkhabaz, Dana E Moseson, Sreya Sarkar, Joachim Brouwers, Garth J Simpson, Patrick Augustijns, Lynne S Taylor
Pages: 2807 - 2820Number of pages: 14 - Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network(2021)
Authors: Zahari Vinarov, Bertil Abrahamsson, Per Artursson, Hannah Batchelor, Philippe Berben, Andreas Bernkop-Schnurch, James Butler, Jens Ceulemans, Nigel Davies, Didier Dupont, et al.
Pages: 289 - 331Number of pages: 43 - Chloroquine, an Anti-Malaria Drug as Effective Prevention for Hantavirus Infections(2021)
Authors: Valentijn Vergote, Lies Laenen, Raf Mols, Patrick Augustijns, Marc Van Ranst, Piet Maes
Number of pages: 10