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Researcher
Patrick Augustijns
- Disciplines:Other pharmaceutical sciences not elsewhere classified
Affiliations
- Drug Delivery and Disposition (Division)
Member
From1 Oct 1999 → 30 Sep 2024
Projects
1 - 10 of 44
- Developing innovative high-resolution liquid chromatography-mass spectrometry (LC-MS) methods to determine the cardio-metabolic effect of foods/mealsFrom5 Aug 2024 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Effect of pH on colloidal structures in human intestinal fluids and intestinal absorption of anticancer drugsFrom1 Sep 2023 → TodayFunding: HORIZON.1.2 - Marie Skłodowska-Curie-actions (MSCA)
- The impact of advanced age and age-related diseases on drug absorptionFrom10 Jan 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mechanistic in silico modelling of colonic drug absorptionFrom1 Dec 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- PBPK modelling of drug absorption in elderlyFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Improving preclinical assays to enhance the prediction of the in vivo behavior of oral drug productsFrom1 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Towards enhanced translational colon-specific in vitro tissue models for assessment of drug disposition, metabolism and safetyFrom23 Sep 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Evaluating the impact of advanced age and age-related diseases on gastrointestinal drug behaviour and on the biochemical barrier of the intestinal mucosaFrom17 May 2021 → 2 Sep 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Drug disposition in healthy volunteers and colorectal cancer patientsFrom1 Apr 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Multi-dimensional liquid chromatography for the analysis of complex samples.From1 Jan 2021 → 31 Dec 2022Funding: BOF - scientific equipment program
Publications
1 - 10 of 365
- Dissolution, phase behavior and mass transport of amorphous solid dispersions in aspirated human intestinal fluids.(2025)
Authors: Joachim Brouwers, Patrick Augustijns
Pages: 336 - 349 - Tofacitinib in Pregnancy: Assessing Pregnancy and Infant Outcomes, Cord Blood, and Breast Milk Concentrations.(2025)
Authors: Patrick Augustijns
Pages: 163 - 165.e3 - Understanding the Impact of Lipids on the Solubilizing Capacity of Human Intestinal Fluids(2024)
Authors: Joachim Brouwers, Patrick Augustijns
Pages: 6398 - 6410 - Ontogeny of Hepatic Organic Cation Transporter-1 in Rat and Human(2024)
Authors: Myriam Baes, Karel Allegaert, Patrick Augustijns, Pieter Annaert
Pages: 1253 - 1261 - A quantification of gastric and duodenal fluid volumes in older adults using MRI.(2024)
Authors: Joachim Brouwers, Patrick Augustijns
Pages: 124831 - The effect of sparkling water on the systemic pharmacokinetics of paracetamol in older adults(2024)
Authors: Fritz Harder, Joachim Brouwers, Tim Vanuytsel, Patrick Augustijns
- Characterization of luminal contents from the fasted human proximal colon.(2024)
Authors: Sebastian Steigert, Joachim Brouwers, Kristin Verbeke, Tim Vanuytsel, Patrick Augustijns
- β-D-N 4-hydroxycytidine (NHC, EIDD-1931) inhibits chikungunya virus replication in mosquito cells and ex vivo Aedes aegypti guts, but not when ingested during blood-feeding(2024)
Authors: Patrick Augustijns, Leen Delang
- The effect of esomeprazole on the upper GI tract release and systemic absorption of mesalazine from colon targeted formulations (Vol 619, 121701, 2022)(2024)
Authors: Tim Vanuytsel, Joachim Brouwers, Patrick Augustijns
- Expression of intestinal drug transporter proteins and metabolic enzymes in neonatal and pediatric patients(2024)
Authors: Joachim Brouwers, Marc Miserez, Ilse Hoffman, Maissa Rayyan, Patrick Augustijns
Patents
1 - 1 of 1
- Permeability model (Inventor)